Results 51 to 60 of about 11,550,226 (340)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

When trust goes wrong: A social identity model of risk taking.

open access: yesJournal of Personality and Social Psychology, 2020
Risk taking is typically viewed through a lens of individual deficits (e.g., impulsivity) or normative influence (e.g., peer pressure). An unexplored possibility is that shared group membership, and the trust that flows from it, may play a role in ...
T. Cruwys   +10 more
semanticscholar   +1 more source

Risk Taking and Force Protection [PDF]

open access: yes, 2011
This paper addresses two questions about the morality of warfare: (1) how much risk must soldiers take to minimize unintended civilian casualties caused by their own actions (“collateral damage”), and (2) whether it is the same for the enemy\u27s ...
Luban, David
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Exploring the effects of risk-taking, exploitation, and exploration on divergent thinking under group dynamics

open access: yesFrontiers in Psychology, 2023
This study examined the effects of risk-taking and exploitation/exploration trade-off on divergent thinking in individuals, dyads, and triads. We adopted a simple Q-learning model to estimate risk attitudes, exploitation, and exploration parameters.
Tsutomu Harada
doaj   +1 more source

FinTech Adoption and Household Risk-Taking

open access: yesSocial Science Research Network, 2020
This paper examines how FinTech can lower investment barriers and help households move toward optimal risk-taking, using a unique account-level data on consumption, investments, and FinTech usage from Ant Group.
C. Hong, Xiaomeng Lu, Jun Pan
semanticscholar   +1 more source

Risk-Taking Behavior and Its Impact on Treatment, Vaccination and Diagnosing [PDF]

open access: yes, 2015
We present results from two recent mathematical biology studies that address the effect of risk-taking behavior on epidemic models. We show that when risk-taking prevails over riskavoidance, it is possible to show a detrimental and counterintuitive ...
Maxin, Daniel
core   +4 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Risk-taking Behaviours among Adolescents (13–19 Years) in Jibannagar, Chuadanga, Bangladesh: A Cross-sectional Study

open access: yesPreventive Medicine: Research & Reviews
Background: Adolescent risk-taking behaviours are a global public health issue. The study aims to explore the proportion, types and factors influencing risk-taking behaviours among adolescents in Jibannagar Upazila, Chuadanga.
Md. Habibur Rahman   +5 more
doaj   +1 more source

Risk as reward: Reinforcement sensitivity theory and psychopathic personality perspectives on everyday risk-taking [PDF]

open access: yes, 2018
This study updates and synthesises research on the extent to which impulsive and antisocial disposition predicts everyday pro- and antisocial risk-taking behaviour.
Andershed   +50 more
core   +4 more sources

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