Results 61 to 70 of about 1,185,926 (248)

Parental Monitoring and Risk-Taking Levels of Adolescents [PDF]

International Journal of School Health, 2023
Ameneh Marzban
doaj   +1 more source

Providence as “Responsible Risk-Taking”

TheoLogica
This paper explores the concept of divine providence in the framework of open theism, focusing on the balance between God’s sovereignty and creaturely libertarian free will.
Johannes Grössl
doaj   +1 more source

Feel Safe to Take More Risks? Insecure Attachment Increases Consumer Risk-Taking Behavior

Frontiers in Psychology, 2019
Attachment styles, originated from early childhood experience, have been documented to influence human behaviors among adults. Drawing on life history theory, we examined whether or not, and how, attachment styles impact risk-taking behaviors beyond ...
Yuanyuan Jamie Li, Su Lu, Junmei Lan, Feng Jiang   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Decision-Making Under Risk, but Not Under Ambiguity, Predicts Pathological Gambling in Discrete Types of Abstinent Substance Users

Frontiers in Psychiatry, 2018
This study explored how different forms of reward-based decision-making are associated with pathological gambling (PG) among abstinent individuals with prior dependence on different classes of drugs.
Michael J. Wilson, Jasmin Vassileva
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

hiv and vulnerability: a comparison of three groups in Cali, Colombia

Revista Facultad Nacional de Salud Pública, 2011
Objetive: to identify socio-demographical characteristics and risk behaviors for hiv /Aids and hiv status in three groups of participants from different socio-economic background in Cali.
Jaime Galindo Q, Inés C. Tello B, Héctor F. Mueses M, Jorge E. Duque M, Gail Shor-Posne, Geraldine Moren   +5 more
doaj  

Unfolding the determinants of university students’ intentions toward digital social entrepreneurship [PDF]

Problems and Perspectives in Management
Digital social entrepreneurship is increasingly receiving recognition in emerging economies to maximize societal benefit. The objective of this study is to examine the factors determining students’ intentions toward digital social entrepreneurial ...
Md. Mobarak Karim, Khadiza Rahman Tanchi, Farhana Noor, Shahana Kabir, Sabrina Akhter   +4 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source