Results 101 to 110 of about 6,297,835 (358)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Risk Assessment and Sustainable Development: Towards a Concept of Sustainable Risk [PDF]
, 1997 Dr. Mehta examines two dominant approaches for managing health and environmental risks and suggests that they would better serve if ...
Mehta, Michael D.
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Risk-Benefit Assessment of Feed Additives in the One Health Perspective [PDF]
, 2022 Alberto Mantovani +3 more
openalex +1 more source
Spatial models for flood risk assessment [PDF]
, 2007 The problem of computing risk measures associated to flood events is extremely important not only from the point of view of civil protection systems but also because of the necessity for the municipalities of insuring against the damages. In this work we
Bee, Marco +2 more
core
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Towards Sustainable Management of Urban Ecological Space: A Zoning Approach Hybridized by Ecosystem Service Value and Ecological Risk Assessment [PDF]
, 2022 Yuzhe Wu, Chenzhuo Gu, Yingnan Zhang
openalex +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Heavy Metal Pollution and Risk Assessment of Surface Dust in the Arid NW China [PDF]
, 2022 Xiuyun Yang +8 more
openalex +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source