Results 141 to 150 of about 17,469,113 (405)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Yellow fever resurgence: An avoidable crisis?

npj Vaccines, 2022
Nicole P. Lindsey, Jennifer Horton, Alan D. T. Barrett, Maurice Demanou, Thomas P. Monath, Oyewale Tomori, Michel Van Herp, Herve Zeller, Ibrahima Soce Fall, Laurence Cibrelus, J. Erin Staples   +10 more
doaj   +1 more source

In vitro and in vivo investigation of a thyroid hormone system-specific interaction with triazoles

Scientific Reports
Alterations in thyroid hormones (TH) and thyroid-stimulating hormone levels are frequently found following exposure to chemicals of concern. Dysregulation of TH levels can severely perturb physiological growth, metabolism, differentiation, homeostasis in
Asya Kadic, Patricia Oles, Benjamin Christian Fischer, Anne Elisabeth Reetz, Boubacar Sidiki Sylla, Katreece Feiertag, Vera Ritz, Tanja Heise, Philip Marx-Stoelting, Tewes Tralau, Kostja Renko, Marize de Lourdes Marzo Solano   +11 more
doaj   +1 more source

Crash risk estimation and assessment tool [PDF]

, 2010
Currently in Australia, there are no decision support tools for traffic and transport engineers to assess the crash risk potential of proposed road projects at design level.
Jurewicz, Chris, Thompson, Bruce
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Environmental risk assessments of uses cyanide in gold extraction on water quality parameters and its effect on rhodanese activities in selected organs of coptodon zillii in igun reservoir, Southwestern, Nigeria [PDF]

, 2022
Oluwakemi Victoria Okunola, Olaniyi Olusola Komolafe, Raphael Emuebie Okonji, Oluwadamilare Emmanuel Obayemi, Sakirat Temitope Asafa, Taiwo Adekanmi Adesakin   +5 more
openalex   +1 more source

Top-down generated micro- and nanoplastics reduce macrophage viability without eliciting a pro-inflammatory response

Microplastics and Nanoplastics
The presence of micro- and nanoplastic particles (MNPs) in our environment, food and drinking water has raised public concern due to inevitable human exposure.
Annemijne E. T. van den Berg, Kas J. Adriaans, Luke A. Parker, Elena M. Höppener, Hanna M. Dusza, Juliette Legler, Raymond H.H. Pieters   +6 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Discovering Innate Driver Variants for Risk Assessment of Early Colorectal Cancer Metastasis [PDF]

, 2022
Ruofan Ding, Yun Zhang, Lvying Wu, Pan You, Zanxi Fang, Zhiyuan Li, Zhongying Zhang, Zhi‐Liang Ji   +7 more
openalex   +1 more source

Technology assessment between risk, uncertainty and ignorance [PDF]

, 2012
The use of most if not all technologies is accompanied by negative side effects, While we may profit from today’s technologies, it is most often future generations who bear most risks.
Hillerbrand, Rafaela
core