Results 141 to 150 of about 16,952,383 (406)

Lipoprotein measurements--a necessity for precise assessment of risk in children from high-risk families [PDF]

, 1979
D Heldenberg, I Tamir, O. Levtow, Yigal Burstein, B. Werbin   +4 more
openalex   +1 more source

Monoamines and assessment of risks

Current Opinion in Neurobiology, 2012
Over the past decade, neuroeconomics studies utilizing neurophysiology methods (fMRI or EEG) have flourished, revealing the neural basis of 'boundedly rational' or 'irrational' decision-making that violates normative theory. The next question is how modulatory neurotransmission is involved in these central processes. Here I focused on recent efforts to
openaire   +3 more sources

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

In vitro and in vivo investigation of a thyroid hormone system-specific interaction with triazoles

Scientific Reports
Alterations in thyroid hormones (TH) and thyroid-stimulating hormone levels are frequently found following exposure to chemicals of concern. Dysregulation of TH levels can severely perturb physiological growth, metabolism, differentiation, homeostasis in
Asya Kadic, Patricia Oles, Benjamin Christian Fischer, Anne Elisabeth Reetz, Boubacar Sidiki Sylla, Katreece Feiertag, Vera Ritz, Tanja Heise, Philip Marx-Stoelting, Tewes Tralau, Kostja Renko, Marize de Lourdes Marzo Solano   +11 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Yellow fever resurgence: An avoidable crisis?

npj Vaccines, 2022
Nicole P. Lindsey, Jennifer Horton, Alan D. T. Barrett, Maurice Demanou, Thomas P. Monath, Oyewale Tomori, Michel Van Herp, Herve Zeller, Ibrahima Soce Fall, Laurence Cibrelus, J. Erin Staples   +10 more
doaj   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Risk Assessment

Journal of Psychiatric Practice, 2020
Hagenlocher, Michael, Thieken, Annegret, Schneiderbauer, Stefan, Aguirre Ayerbe, Ignacio, Dobes, Pavel, Donovan, Amy, Morsut, Claudia, Paris, Nicholas, Pedoth, Lydia, Tonmoy, Fahim   +9 more
openaire   +5 more sources

Design and initial validation of the Raster method for telecom service availability risk assessment [PDF]

, 2012
Crisis organisations depend on telecommunication services; unavailability of these services reduces the effectiveness of crisis response. Crisis organisations should therefore be aware of availability risks, and need a suitable risk assessment method ...
Etalle, Sandro, Vriezekolk, Eelco, Wieringa, Roel   +2 more
core   +1 more source

Top-down generated micro- and nanoplastics reduce macrophage viability without eliciting a pro-inflammatory response

Microplastics and Nanoplastics
The presence of micro- and nanoplastic particles (MNPs) in our environment, food and drinking water has raised public concern due to inevitable human exposure.
Annemijne E. T. van den Berg, Kas J. Adriaans, Luke A. Parker, Elena M. Höppener, Hanna M. Dusza, Juliette Legler, Raymond H.H. Pieters   +6 more
doaj   +1 more source