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A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Antibiotics and pesticides are widespread in most rivers and lakes due to the overuse of antibiotics and pesticides, but there are few methods for simultaneous analysis of antibiotics and pesticides in aquatic environments. To address this knowledge gap,
Xiang-Pu Zhang+8 more
doaj +1 more source
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
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Does Lost Time Cost You Money and Create High Risk? [PDF]
The aim of the case study is to express the delayed repair time impact on the revenues and profit in numbers with the example of the outage of power plant units.
Fekete, István
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Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
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Rapid detection of iprodione in cucumber and apple using an immunochromatographic strip test
In recent years, fungicides have been frequently detected in soil, water, and air because of their extensive use, with detrimental effects on the environment. Therefore, the screening of foods for iprodione (IPRO) has become mandatory.
Pengjie Luo+4 more
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Predictive validity of the Short-Term Assessment of Risk and Treatability (START) for multiple adverse outcomes:the effect of diagnosis [PDF]
The Short-Term Assessment of Risk and Treatability (START) assists risk assessment for seven risk outcomes based on scoring of risk and protective factors and assignment of clinically-informed risk levels.
Dickens, Geoffrey L+3 more
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Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
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Micro- and nanoplastics (MNP) are ubiquitously present in the environment due to their high persistence and bioaccumulative properties. Humans get exposed to MNP via various routes and consequently, they will encounter dendritic cells (DC) which are ...
Annemijne E. T. van den Berg+7 more
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ISER 2012 Working Paper No. 1 [PDF]
Large resource development projects take years to plan. During that planning time, the public frequently debates the potential benefits and risks of a project, but with incomplete information.
Loeffler, Bob
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