Results 71 to 80 of about 11,921,480 (304)

The impact of flooding on people living with HIV: a case study from the Ohangwena Region, Namibia [PDF]

Global Health Action, 2015
Background: Floods are a disaster situation for all affected populations and especially for vulnerable groups within communities such as children, orphans, women, and people with chronic diseases such as HIV and AIDS.
Carmen Anthonj, Odon T. Nkongolo, Peter Schmitz, Johannes N. Hango, Thomas Kistemann   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Healthcare beliefs, health information seeking, and healthcare setting preferences among women who inject drugs by community supervision status

Health & Justice, 2021
Objective Women on community supervision who inject drugs have significant unmet healthcare needs. However, it remains unclear how the intersection of community supervision and injection drug use influences healthcare experiences and service setting ...
Ariel Hoadley, Sarah Bauerle Bass, Jesse Brujaha, Paul A. D’Avanzo, Patrick J. Kelly   +4 more
doaj   +1 more source

Operational framework for flood risk communication

, 2020
Risk communication is a mutual process of understanding the risk among stakeholders and represents a measure to integrate lay knowledge into measures to prevent, mitigate, and deal with risk.
E. Intrieri, Giulia Dotta, Katia Fontanelli, Chiara Bianchini, F. Bardi, Federico Campatelli, N. Casagli   +6 more
semanticscholar   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Between financial, environmental and health concerns: the role of risk perceptions in modeling efuel acceptance

Frontiers in Energy Research
The transition towards sustainable and defossilized mobility systems relies on public perception and acceptance of innovations like efuels. Understanding the role of risk perceptions and their different dimensions in shaping public acceptance is ...
Katrin Arning, Julia Offermann, Linda Engelmann, Regina Gimpel, Martina Ziefle   +4 more
doaj   +1 more source

Achieving the promise of digital health information systems

Journal of Public Health Research, 2014
not ...
Gary L. Kreps
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

What’s in my fuel tank? Insights into beliefs and preferences for e-fuels and biofuels

Energy, Sustainability and Society, 2023
Background Alternative fuels made from biomass or CO2 and water using renewable energy can reduce CO2 and pollutant emissions compared to fossil-based mobility and thus support a transition to a more sustainable transport.
Anika Linzenich, Dominik Bongartz, Katrin Arning, Martina Ziefle   +3 more
doaj   +1 more source