Results 71 to 80 of about 825,360 (268)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Agents of sustainable change: the importance of leadership and responsibility in corporate sustainability

Frontiers in Sustainability
IntroductionAddressing climate change requires both individual behavioral change and corporate transformation, as organizations play a crucial role in a sustainable society.
Maike Keil, Valerie Michaux, Martina Ziefle, Katrin Arning   +3 more
doaj   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Evaluating the Readability of Patient‐Facing Online Educational Materials for Pediatric Leukemia and Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Together, leukemia and lymphoma account for 38.7% of newly diagnosed pediatric cancer cases in the United States each year. Many caregivers utilize online resources to inform medical health decisions. Understanding the readability of these materials is critical to ensuring comprehensible patient education.
Chloe Strege, Simone Intriago Tito, Courtney Popp, William C. Miller, Cindy Eide, Christen Ebens, Jakub Tolar   +6 more
wiley   +1 more source

Empowerment amidst turmoil, the association between protest participation against the 2023 Israeli judicial reform, individual perceived threats, and civic empowerment (self-efficacy): a cross-sectional online survey

Frontiers in Political Science
BackgroundProtests serve as a powerful catalyst for transformations, where collective influence can lead to significant personal changes. Collective action can strengthen empowerment and collective self-efficacy in facing threats.
Anat Gesser-Edelsburg, Rana Hijazi, Ester Eliyahu, Ricky Cohen   +3 more
doaj   +1 more source

Achieving the promise of digital health information systems

Journal of Public Health Research, 2014
not ...
Gary L. Kreps
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Chances and risks in medical risk communication

German medical science : GMS e-journal, 2015
Communication between physicians and patients in everyday life is marked by a number of disruptive factors. Apart from specific interests, mistakes, and misunderstandings on both sides, there are main factors that contribute to the risk in risk communication.
Hoffrage, U., Koller, M.
openaire   +6 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Farm Animal Welfare on the Mind and Meat in the Diet: Who Are These Consumers?

Animals
We investigated the association between farm animal welfare (FAW) concern and self-classified meat consumption behavior and consumers’ socio-demographic, animal-contact-related, and ideological background factors.
Mariske P. Hajer, Jeroen Borghuis, Job M. Molendijk, Joost Meekes, Antoon Opperhuizen   +4 more
doaj   +1 more source