Results 41 to 50 of about 7,503,171 (257)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Monte Carlo methods for the estimation of value-at-risk and related risk measures [PDF]

, 2011
Nested Monte Carlo is a computationally expensive exercise. The main contributions we present in this thesis are the formulation of efficient algorithms to perform nested Monte Carlo for the estimation of Value-at-Risk and Expected-Tail-Loss.
Marks, Dean
core   +1 more source

Associations of long-term exposure to ambient sulfur dioxide, carbon monoxide, ozone, and benzene with risk of incident chronic kidney disease in the UK

Environmental Research Letters
Limited studies have examined associations of gaseous air pollutants exposure with chronic kidney disease (CKD) in Europe. This study aimed to calculate the relationships between long-term exposure to ambient sulfur dioxide (SO _2 ), carbon monoxide (CO),
Feifei Zhang, Yuhao Liu, Chao Yang, Fulin Wang, Luxia Zhang   +4 more
doaj   +1 more source

Consequence Analysis of LNG Leaks During Offloading Operations: Effects of Substrate Types, Atmospheric Conditions, and Basic Process Control System Intervention

IEEE Access, 2019
With the increasing demands for liquefied natural gas (LNG), more and more LNG terminals are being constructed, and the risk of leakage during LNG off-loading processes has been given increasing amounts of attention.
Xiaoyun Zheng, Guoming Chen, Jianmin Fu, Xiaodong Zhang, Zhiqian Xu   +4 more
doaj   +1 more source

Simplified Approach to Predicting Obstructive Coronary Disease With Integration of Coronary Calcium: Development and External Validation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background The Diamond‐Forrester model was used extensively to predict obstructive coronary artery disease (CAD) but overestimates probability in current populations.
Robert J. H. Miller, Heidi Gransar, Alan Rozanski, Damini Dey, Mouaz Al‐Mallah, Benjamin J. W. Chow, Philipp A. Kaufmann, Filippo Cademartiri, Erica Maffei, Donghee Han, Piotr J. Slomka, Daniel S. Berman   +11 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Occupational exposure to organic solvents and the risk of developing testicular germ cell tumors (TESTIS study): Effect of combined exposure assessment on risk estimation

Scandinavian Journal of Work, Environment & Health
OBJECTIVES: Etiological factors of testicular germ cell tumors (TGCT) remain largely unknown, but a causal role of occupational exposures to solvents has been suggested.
Margot Guth, Corinne Pilorget, Marie Lefevre, Astrid Coste, Aurélie Danjou, Brigitte Dananché, Delphine Praud, Olivia Pérol, Myriam Daudin, Marie-Ange Clarotti, Stéphanie Lattes, Céline Bouillon, Adèle Paul, Joachim Schüz, Louis Bujan, Ann Olsson, Béatrice Fervers, Barbara Charbotel, The TESTIS study group   +18 more
doaj   +1 more source

Monte Carlo modeling of the Yttrium-90 nanospheres application in the liver radionuclide therapy and organs doses calculation [PDF]

Nuclear Technology and Radiation Protection, 2016
Using the nano-scaled radionuclides in the radionuclide therapy significantly reduces the particles trapping in the organs vessels and avoids thrombosis formations. Additionally, uniform distribution in the target organ may be another benefit of
Ghavami Seyed Mostafa, Ghiasi Hosein, Mesbahi Asghar   +2 more
doaj   +1 more source

SCORE2-diabetes : 10-year cardiovascular risk estimation in type 2 diabetes in Europe [PDF]

, 2023
Aims: To develop and validate a recalibrated prediction model (SCORE2-Diabetes) to estimate the 10-year risk of cardiovascular disease (CVD) in individuals with type 2 diabetes in Europe.Methods and results: SCORE2-Diabetes was developed by extending ...
Azzopardi, Joseph, SCORE2-Diabetes Working Group, Magri, Caroline Jane, ESC Cardiovascular Risk Collaboration   +3 more
core   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source