Results 131 to 140 of about 12,559,419 (309)
Factor reduction and clustering for operational risk in software development
, 2014 Software development failures frequently emerge as a result of the failure to understand and to identify risks. The aim of this paper is to identify the most salient risk factors during a software development project lifecycle, in terms of occurrence ...
Abdul-Rahman, H +4 more
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The factor VII activating protease G511E (Marburg) variant and cardiovascular risk [PDF]
, 2004 A previous study had shown a strong relationship between a variant in factor VII activating protease (FSAP G511E) and advanced carotid atheroma. In-vitro, the variant has reduced fibrinolytic but normal pro-coagulant activity, which may constitute a ...
Ireland, H. +4 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On the interaction between market and credit risk: a factor-augmented vector autoregressive (FAVAR) approach [PDF]
The aim of the paper is to understand the interaction between market and credit risk. Using a comprehensive set of Italian data, we apply a factor model to identify the common sources of risk driving fluctuations in the real and financial sectors.
Simonetta Iannotti, Roberta Fiori
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Other title: Behavioral Risk Factor Surveillance System, 2011
, 2012 December 2012Behavioral Risk Factor Surveillance System Overview -- Leading Health Indicators -- Physical Activity -- Obesity -- Tobacco Use -- Substance Abuse -- Injury and Violence -- Immunizations -- Access to Health Care -- Featured Issues in 2003 ...
Kansas. Office of Health Promotion; Kansas. Department of Health and Environment
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Other title: Behavioral Risk Factor Surveillance System, 2003
, 2005 November 2005; application/pdfBehavioral Risk Factor Surveillance System Overview -- Leading Health Indicators -- Physical Activity -- Obesity -- Tobacco Use -- Substance Abuse -- Injury and Violence -- Immunizations -- Access to Health Care -- Featured ...
Kansas. Office of Health Promotion; Kansas. Department of Health and Environment
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Other title: Behavioral Risk Factor Surveillance System, 2010
, 2011 December 2011Behavioral Risk Factor Surveillance System Overview -- Leading Health Indicators -- Physical Activity -- Obesity -- Tobacco Use -- Substance Abuse -- Injury and Violence -- Immunizations -- Access to Health Care -- Featured Issues in 2003 ...
Kansas. Office of Health Promotion; Kansas. Department of Health and Environment
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