Results 151 to 160 of about 24,883,480 (353)

Systematic credit risk: CDX index correlation and extreme dependence. [PDF]

Dependence is an important issue in credit risk portfolio modeling and pricing. We discuss a straightforward common factor model of credit risk dependence, which is motivated by intensity models such as Duffie and Singleton (1998), among others.
Aboura, Sofiane, Wagner, Niklas
core  

Atrial fibrillation as an independent risk factor for stroke: the Framingham Study.

Stroke, 1991
P. Wolf, R. Abbott, W. Kannel
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Multimodal pulmonary clearance kinetics of carbon black nanoparticles deposited in the lungs of rats: the role of alveolar macrophages

Particle and Fibre Toxicology
Background Alveolar macrophages (AMs) have been predicted to affect the pulmonary clearance of nanomaterials; however, their qualitative and quantitative roles are poorly understood.
Dong-Keun Lee, Gyuri Kim, Muthuchamy Maruthupandy, Kyuhong Lee, Wan-Seob Cho   +4 more
doaj   +1 more source

Nicotinamide adenine dinucleotide phosphate oxidase 2 deletion attenuates polyhexamethylene guanidine-induced lung injury in mice

Heliyon
Inhalation of polyhexamethylene guanidine phosphate (PHMG) can cause pulmonary fibrosis. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox) are enzymes that produce reactive oxygen species, which may be involved in tissue damage in ...
Yoon Cho, Seulgi Jeon, Sung-Hwan Kim, Hyeon-Young Kim, Bumseok Kim, Mi-Jin Yang, Jinhyung Rho, Moo-Yeol Lee, Kyuhong Lee, Min-Seok Kim   +9 more
doaj   +1 more source

Understanding Liquidity and Credit Risks in the Financial Crisis* [PDF]

This paper develops a structured dynamic factor model for the spreads between London Interbank Offered Rate (LIBOR) and overnight index swap (OIS) rates for a panel of banks. Our model involves latent factors which relect liquidity and credit risk.
Deborah Gefang, Gary Koop, Simon Potter
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A multicenter prospective randomized controlled trial investigating the effects of combustion-free nicotine alternatives on cardiovascular risk factors and metabolic parameters in individuals with type 2 diabetes who smoke: the DiaSmokeFree study protocol [PDF]

, 2023
Arkadiusz Krysiński, Cristina Russo, Davide Campagna, Antonino Di Pino, Sarah John, Jonathan Belsey, Pasquale Caponnetto, Lorina Vudu, Chong Wei Lim, Agostino Di Ciaula, Nicola Veronese, Mario Barbagallo, Farrukh Iqbal, David Fluck, Edward Franek, Riccardo Polosa, Pankaj Sharma, the DiaSmokeFree investigators   +17 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The impact of social isolation and loneliness on cardiovascular disease risk factors: a systematic review, meta-analysis, and bibliometric investigation [PDF]

Osama Albasheer, Siddig İbrahim Abdelwahab, Mohammad Zaino, Ahmed Abdallah Ahmed Altraifi, Nasser Hakami, Ehab I. El-Amin, Mohammed M. Alshehri, Saeed M. Alghamdi, Abdulfattah S. Alqahtani, Aqeel M. Alenazi, Bader A. Alqahtani, Ahmed Alhowimel, Shadab Uddin, Husam Eldin Elsawi Khalafalla, Isameldin Elamin Medani   +14 more
openalex   +1 more source