Results 101 to 110 of about 9,263,992 (362)

Research progress on ultra-processed foods consumption and its association with health

环境与职业医学
With the rapid progress of industrialization and commercialization, the sales and population intake of ultra-processed foods (UPFs) are constantly increasing globally. High UPFs intake is associated with various health issues.
Jiaqian ZHONG, Jiangyue YU, Zhengyuan WANG, Zhuo SUN, Jiajie ZANG   +4 more
doaj   +1 more source

Factors Associated with Increased Risk of Overweight and Obesity in Children: An Evidence from Boyolali, Central Java [PDF]

, 2018
Background: Childhood obesity is a major public health challenge both in developed and developing countries. The prevalence of childhood obesity has increased over few years. It is caused by imbalance between calorie intake and calories utilized.
Dewi, Y. L. (Yulia ), Salimo, H. (Harsono ), Wijayanti, D. (Dwi )   +2 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Capturing Scientific Knowledge on Medical Risk Factors [PDF]

, 2015
In this paper, we describe a model for representing scientific knowledge of risk factors in medicine in an explicit format which enables its use for automated reasoning. The resulting model supports linking the conclusions of up-to-date clinical research
Domingue, John, Gkotsis, George, Kaldoudi, Eleni, Pafili, Kalliope, Roumeliotis, Stefanos, Third, Allan   +5 more
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Photocatalytic Bilateral Disulfuration of Thioethers Toward α‐Sulfide Disulfides With Antibacterial Activity

Advanced Science
α−Sulfide disulfides represent valuable motifs in organic and pharmaceutical chemistry. However, the limited availability of synthetic approaches for α−sulfide disulfides has impeded progress in this field.
Qingqiang Tian, Chuxia Wang, Bingrui Liu, Xiangwei Wu, Yahui Li   +4 more
doaj   +1 more source

Risk Factors for Spontaneous Bacterial Peritonitis in Patients with Liver Cirrhosis and Ascites [PDF]

, 2002
Spontaneous bacterial peritonitis (SBP) is one of serious complication of liver cirrhosis. Most of the patient with SBP have severe reduced liver function that clasified as Child Plugh class C.
Djojoningrat, D. (Dharmika), Noer, S. (Sjaifoellah), Razy, F. (Fachrul), Sukmana, N. (Nanang)   +3 more
core   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Changes in the Physicochemical Properties and Microbial Communities of Air-Fried Hairtail Fillets during Storage

Foods
This study assessed the physicochemical properties of air-fried hairtail fillets (190 °C, 24 min) under different storage temperatures (4, 25, and 35 °C).
Yixuan Ding, Yueqin Liao, Jiangyue Xia, Disha Xu, Menghua Li, Hongli Yang, Huimin Lin, Soottawat Benjakul, Bin Zhang   +8 more
doaj   +1 more source

Early life factors and risk of childhood rhabdomyosarcoma. [PDF]

, 2013
Although little is known about etiology of childhood rhabdomyosarcoma (RMS), early life factors are suspected in the etiology. We explored this hypothesis using linked data from the California Cancer Registry and the California birth rolls.
Anshu eShrestha, Anshu eShrestha, Beate eRitz, Christina A Lombardi, Julia eHeck, Michelle eWilhelm, Simona eOgnjanovic   +6 more
core   +2 more sources