Results 131 to 140 of about 9,263,992 (362)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Prevalence and risk factors of HIV in Faisalabad, Pakistan- A retrospective study [PDF]

, 1969
Muhhamad Arif Mann, Fatma Hussain, Muhhamad Jamil   +2 more
openalex   +1 more source

Identifying the Ergonomic Risk Factors of a Job [PDF]

, 2019
[Excerpt] When we experience overexertion of muscles and joints, common symptoms include soreness, pain, discomfort, redness and swelling, limited range of motion, stiffness in joints, weakness and clumsiness, numbing/ tingling sensations (“pins and ...
Brown, Nellie J
core   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Dietary habits, lifestyles, and overall adherence to 2018 WCRF/AICR cancer prevention recommendations among adult women in the EPIC-Florence cohort: Changes from adulthood to older age and differences across birth cohorts

The Journal of Nutrition, Health and Aging
Objectives, setting and participants: We aimed to examine changes in dietary habits, lifestyles (e.g., smoking, physical activity levels, and alcohol intake), anthropometry, other individual health-relevant characteristics, and overall adherence to 2018 ...
Saverio Caini, Melania Assedi, Benedetta Bendinelli, Ilaria Ermini, Luigi Facchini, Miriam Fontana, Davide Liedl, Domenico Palli, Elisa Pastore, Andrea Querci, Calogero Saieva, Giovanna Masala   +11 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Effects of Different Pretreatment on Curcumin-mediated Photodynamic Inactivation and Preservation of Large Yellow Croaker (Larimichthys crocea)

Shipin gongye ke-ji
In order to investigate the effect of different pretreatment methods on the preservation efficacy of curcumin-mediated photodynamic inactivation (PDI) for aquatic products, four pretreatment methods were evaluated for their PDI preservation effect on ...
Shuyi ZHAO, Jilong NI, Yutong QU, Long JIAO, Xiaoye ZHANG, Bin ZHANG   +5 more
doaj   +1 more source

Risk Factors Affecting Multi-Drug Resistant Tuberculosis in Surakarta and Ngawi, Indonesia [PDF]

, 2016
Background: The success rate of Tuberculosis treatment in Indonesia decreased by 81.3% in 2014, which below the 85% target. The current increasing problem in the developing world is multidrug resistance of Tuberculosis (MDR-TB).
Aderita, N. I. (Novi), Murti, B. (Bhisma), Suryani, N. (Nunuk)   +2 more
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Associations of serum arginine acid with sarcopenia in Chinese eldely women

Nutrition & Metabolism
Background The prevalence of sarcopenia is increasing in worldwide with accelerated aging process. The high dietary protein intakes are associated with improved muscle mass and strength especially in Asian countries.
Chao Hua, Yuhua Chen, Zhuo Sun, Zehuan Shi, Qi Song, Liping Shen, Wei Lu, Zhengyuan Wang, Jiajie Zang   +8 more
doaj   +1 more source