Results 101 to 110 of about 6,445,882 (303)

Assessing the Performance of Development of Scintillometers under Different Environmental Conditions

Gaoyuan qixiang
Based on field observation data from the A'rou and Daman stations in the Heihe River Basin between 2016 and 2022， this study analyzes the technical performance of domestically developed near-infrared scintillometers （LAS） and dual-band scintillometers ...
Mengyue OUYANG, Ziwei XU, Shaomin LIU
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The Energy–Water–Land Nexus of Global Water‐Surface Solar Photovoltaics

Earth's Future
Photovoltaic (PV) power generation, as a low‐cost and clean energy technology, has become one of the most sustainable renewable energy sources. Water‐surface photovoltaic (WSPV) systems exhibit a unique synergy in clean energy generation, water ...
Anqi Li, Jidong Wu
doaj   +1 more source

Can trust be restored to high-street banking: A 20-year challenge?

Cogent Business & Management, 2017
This article is based on a dissertation submitted for an MSc in Marketing submitted by the first author and supervised by the second author. It is a viewpoint article that highlights the complexity of the challenge of restoring trust to high-street ...
Peter McCormack, Jonathan Deacon
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Factors Influencing Wild Venison Consumption in Illinois

Animals
Venison serves as a sustainable alternative to conventional protein sources and is closely tied to wildlife conservation efforts. This study sought to identify key factors influencing wild game consumption.
Huicheng Chen, Xiaohan Zhang, Junjie Wan, Craig A. Miller   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

From extreme days to event-scale persistence: Characterizing for persistent extreme precipitation across multisource datasets

Weather and Climate Extremes
Persistent extreme precipitation (PEP) events pose increasing hydrological and societal risks, yet their event-scale characterization remains incomplete because conventional analyses often emphasize extreme days while neglecting the non-extreme rainfall ...
Zihui Zhao, Shuiqing Yin, Daoyi Gong
doaj   +1 more source

Risk and Value: two sides of the same coin.

, 2017
Il controllo dei rischi come strumento di creazione del ...
COCOZZA, ROSA
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source