Results 81 to 90 of about 6,445,882 (303)

Complexity, Governance and Networks: Introduction to the Inaugural Issue

, 2014
From the introduction: 1. Yet Another Journal? Why is it necessary to publish a new journal about complexity, governance, and networks? There has been an increasing interest in complexity, governance, and network studies in recent decades.
Morçöl, Göktuğ, Gerrits, Lasse, Teisman, Geert   +2 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Adaptive Governance and sub-national Climate Change Policy: A comparative analysis of Khyber Pukhtunkhawa and Punjab Provinces in Pakistan

, 2019
This study explores the adaptive governance and effective implementation of climate policies at the subnational level in a developing country context. We focused on Pakistan as our central case as it is considered one of the most vulnerable countries to ...
H. Ali, Saleem, Mumtaz, Muhammad
core   +1 more source

Social Learning in Multilevel Flood Risk Governance: Lessons from the Dutch Room for the River Program [PDF]

, 2019
Although social learning is a key element of multilevel flood risk governance, it is hardly studied. This paper addresses this knowledge gap. The paper aims to identify enabling conditions for social learning in multilevel flood risks governance ...
Dieperink, C., Mukhtarov, F. (Farhad), Farhad Mukhtarov, Environmental Governance, Jacomien den Boer, Dieperink, C. (Carel), den Boer, Jacomien, Dieperink, Carel, den Boer, J. (Jacomien), den Boer, J., Carel Dieperink, Dieperink, C, Mukhtarov, Farhad, Boer, Jacomien, Mukhtarov, F.   +14 more
core   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Quantitative assessment method of typhoon-induced photovoltaic damage and energy production losses: a case study of the 2024 Typhoon Yagi

Geomatics, Natural Hazards & Risk
Climate change has intensified the threat of typhoons to photovoltaic (PV) infrastructure. We present a quantitative assessment method to conduct typhoon-induced PV infrastructure loss assessment.
Anqi Li, Jidong Wu
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

AHAD: African major crops harvested area dataset for the years of 2000, 2010, and 2020

Scientific Data
Africa faces significant challenges in food security, which are compounded by rapid population growth. The situation is expected to worsen without effective interventions.
Wenmeng Zhang, Hui Zhang, Fang Wu, Hengbin Yu, Lijun Zuo, Xuefeng Cui   +5 more
doaj   +1 more source

Corporate governance, sustainability and the assessment of default risk [PDF]

, 2009
This paper investigates whether the quality of a firm’s corporate governance practices and its sustainability disclosures are inversely related to its assessed default risk. It is expected that high reported standards of corporate governance will reduce
Cotter, Julie, James-Overheu, Christina
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source