Results 61 to 70 of about 6,445,882 (303)

Global governance by goal-setting: the novel approach of the UN Sustainable Development Goals: Open issue, part II [PDF]

, 2017
The 17 Sustainable Development Goals (SDGs) of the United Nations present a novel approach to global governance where goal-setting features as a key strategy.
Global Sustainability Governance, Environmental Governance, Biermann, Frank, Kanie, Norichika, Kim, Rak   +4 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Developing an evaluation tool for the impact of consumer partnerships in healthcare governance: a coproduced mixed methods study

BMJ Open Quality
Background Consumer partnerships are a recent innovation in healthcare governance to diversify decision-making perspectives. These partnerships bring complexity necessitating comprehensive evaluation.
Ruth Cox, Jodie Nixon, Rae Parker, Faiza El-Higzi, Melanie Lynch   +4 more
doaj   +1 more source

Risk Governance and Bank Risk of Public Commerical Banks of OECD

This study investigates the impact of risk governance on bank risk within the Organisation for Economic Co-operation and Development (OECD) public commercial banks.
Malik, Muddassar
core   +1 more source

Responsive Governance and Harmful Microbial Blooms on Lake Erie: An ABM Approach

, 2019
In general, decision makers tend to respond to problems rather than prevent them. In political science, this process of responsive governance is associated with complex dynamics such as availability cascades and punctuated equilibrium.
Pavlovich, Tyler, Webster, DG
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Rising worldwide challenges to climate-induced extreme low-production events of photovoltaic and wind power

Nature Communications
The global shift toward solar photovoltaic (PV) and wind power is crucial to climate mitigation, yet climate change may intensify extreme low-production (ELP) events and affect power reliability.
Qianzhi Wang, Kai Liu, Ming Wang, Zhao Zhang, Hao Chen, Lancui Liu, Jinshan Wu, Heran Zheng   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

High-resolution soil moisture retrieval in heterogeneous terrain: A comparison of ensemble learning approaches using landsat 8/9

Journal of Hydrology: Regional Studies
Study region: The study area is located in Tianjun County, eastern Qinghai Province, China, near Qinghai Lake on the northwestern Qinghai-Tibet Plateau, covering approximately 40 × 36 km.
Qingxia Wu, Zhongli Zhu, Julong Ma, Shaomin Liu, Linna Chai, Ziwei Xu   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source