Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Incorporating compound temporal precipitation dynamics to enhance landslide susceptibility modeling
npj Natural HazardsPrecipitation plays a crucial role in landslides, which most studies have disregarded the impact of compound temporal precipitation. Here, we developed models that incorporate compound temporal precipitation, constructed by jointly characterizing long ...
Jingjing Wang +3 more
doaj +1 more source
Land Use Change in the Russian Far East and Its Driving Factors
LandThis study systematically analyzes land use changes in the Russian Far East from 2000 to 2020, identifying key transformations and their driving factors.
Cong Wang, Xiaohan Zhang, Liwei Liu
doaj +1 more source
Corporate governance and risk reporting in South Africa: a study of corporate risk disclosures in the pre- and post-2007/2008 global financial crisis period [PDF]
, 2012 The 2007/2008 global financial crisis has reignited the debate regarding the need for effective corporate governance (CG) through sound risk management and reporting practices.
Ntim, Collins G. +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Planning Adaptive Risk Regulation [PDF]
This report comprises a summary of the contributions made at a conference in 2016. The conference was conveyed to discuss two main questions: (1) how can law and regulation keep up with advances in science and technology, and (2) how can regulated ...
EPFL, International Risk Governance Center
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Global land system maps at 1 km resolution for 1.5 °C climate
Scientific DataClimate pledges are a key pathway for achieving temperature control but also exert profound cascading effects on the global Earth system. Evaluating such cascading effects often requires land change forecast products.
Yifan Gao +9 more
doaj +1 more source
FloodKAN: Integrating Kolmogorov–Arnold Networks for Efficient Flood Extent Extraction
Remote SensingFlood events are among the most destructive natural catastrophes worldwide and pose serious threats to socioeconomic systems, ecological environments, and the safety of human life and property. With the advancement of remote sensing technology, synthetic
Cong Wang, Xiaohan Zhang, Liwei Liu
doaj +1 more source
Towards a diversification of Flood Risk Management in Europe: a reflection on meta-governance challenges [PDF]
, 2014 Because of climate change, extreme weather events and urban sprawl, urban areas have to deal with increasing flood risks. It is argued, both in literature and in practice that these risks can no longer be dealt with by focusing solely on flood defences ...
Dieperink, C. +4 more
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