Results 71 to 80 of about 12,589,259 (348)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Correcting correlation quality of portable X-ray fluorescence to better map heavy metal contamination by spatial co-kriging interpolation

Ecotoxicology and Environmental Safety
High-precision mapping based on portable X-ray fluorescence (PXRF) data is currently being studied extensively; however, owing to poor correlation with soil metal concentration, the original PXRF data directly used for co-kriging interpolation (CKI ...
Manying Zhao, Zengsiche Chen, Can Qian, Yuxin Zhao, Ya Xu, Yuqiang Liu   +5 more
doaj   +1 more source

A data-driven approach to identify-quantify-analyse construction risk for Hong Kong NEC projects

Journal of Civil Engineering and Management, 2018
Project risks must be managed to deliver construction projects on time and within budget. In recent years, the New Engineering Contract (NEC) provides an alternate contracting method for procuring construction projects. As stipulated in the NEC contract,
Ming-Fung Francis Siu, Wing-Yan Jacqueline Leung, Wai-Ming Daniel Chan   +2 more
doaj   +1 more source

RISK MANAGEMENT IN PRODUCT DEVELOPMENT: RISK IDENTIFICATION, ASSESSMENT, AND MITIGATION – A LITERATURE REVIEW

Proceedings of the Design Society: DESIGN Conference, 2020
This paper reviews the literature on risk management practices and methods in product design and development. Based on an expert workshop by the Risk Management Processes and Methods in Design Special Interest Group within the Design Society and ...
J. Oehmen, A. Guenther, J. W. Herrmann, J. Schulte, P. Willumsen   +4 more
semanticscholar   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Development of a novel method for cross-disciplinary hazard identification [PDF]

, 2013
Hazards and risks are currently identified in generic risk silos using top-down tools and methods which are incorporated into whole system risk management frameworks such as enterprise risk management.
Parchment, Ann
core  

Transgenerational hepatotoxicity induced by bisphenol B as a substitute for bisphenol A

Ecotoxicology and Environmental Safety
Accumulating evidence identifies bisphenol A (BPA) as an endocrine disruptor with demonstrated hepatotoxicity, driving the adoption of structural analogs like bisphenol B (BPB).
Huifeng Yue, Yangcheng Hu, Xiaoyun Wu, Yuchai Tian, Xiaomin Liang, Jiyue Zhang, Bin Li, Huizhen Zhu, Xiaotong Ji   +8 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Research on the pollution characteristics of typical hazardous wastes in the non-ferrous smelting industry

能源环境保护
The National Catalogue of Hazardous Wasteis the primary legal document for identifying hazardous wastes and also provides the foundation for its environmental management in China. The non-ferrous smelting industry involves a complex process with numerous
WANG Fei, LI Xuebing, HUANG Qifei* , YANG Yufei   +3 more
doaj   +1 more source

Risk identification framework in construction of Egyptian mega housing projects

Ain Shams Engineering Journal, 2020
Egypt's population is increasing and expected to exceed 120 million by 2050. Egypt constructed mega housing projects (M.H.P) to cater with that escalation in population. The Egyptian strategy 2030 prioritized the construction of M.H.P.
Mohamed Nabawy, G. Ofori, M. Morcos, C. Egbu   +3 more
semanticscholar   +1 more source