Results 91 to 100 of about 19,656,854 (402)

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Haste, Pressure and Staffing Shortages Contribute to Costly Mistakes

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Mathematical model of immune and neuroendocrine systems functioning with regard to evolution of organ synthetic function violations

Analiz Riska Zdorovʹû, 2015
Currently, the concept of a “three-pronged” regulatory “metasystem”, which includes the immune and neuroendocrine regulation circuits, is well recognized.
D.A. Kiryanov, D.V. Lanin, V.M. Chigvintsev   +2 more
doaj   +1 more source

Investigating the relationship between supply chain innovation, risk management capabilities and competitive advantage in global supply chains

, 2018
The purpose of this paper is to propose and validate a theoretical model to investigate whether supply chain (SC) innovation positively affects risk management capabilities, such as robustness and resilience in global SC operations, and to examine how ...
Dong-Wook Kwak, Youngin Seo, R. Mason
semanticscholar   +1 more source

Enterprise Risk Management Practices and Firm Performance, the Mediating Role of Competitive Advantage and the Moderating Role of Financial Literacy

Journal of Risk and Financial Management, 2018
In the current turbulent market, firms spend lots of tangible and intangible resources to gain competitive advantage and superior performance. Prior studies have discussed several determinants of competitive advantage and performance, particularly in ...
Songling Yang, Muhammad Ishtiaq, M. Anwar   +2 more
semanticscholar   +1 more source

A Complexity Science Based Approach to Programme Risk Management [PDF]

, 2008
Programme management has rapidly gained acceptance as a vehicle for achieving organisational strategic objectives and as a means of aligning projects with the overall strategy of the organisation.
Aritua, B., Bower, D.A., Smith, N.J.
core  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Seek Guidance for Complex Practice Challenges: Ethics, Financial Protection and Employee Relations

Journal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Disaster-induced displacement in the Caribbean and the Pacific

Forced Migration Review, 2017
People in Small Island Developing States are particularly vulnerable to displacement by disaster. Governments in the Caribbean and the Pacific need urgently to do more risk management and planning, rather than focusing almost exclusively on response and ...
Mo Hamza, Ida Koch, Malte Plewa
doaj  

To Risk or Not to Risk? Risk Management and Farm Productivity

American Journal of Agricultural Economics, 2019
The impact of risk management on farm productivity is still being debated. Using survey data from French and Hungarian farms, we estimate the impacts of different risk management strategies and portfolios under varying levels of risk on total factor ...
M. Vigani, Jonas Kathage
semanticscholar   +1 more source