Results 111 to 120 of about 6,723,402 (312)
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Multidimensional food security in North Eastern Amhara: a CARI based agroecological analysis
Discover SustainabilityThe North Eastern Amhara Region is prone to drought, making the pursuit of food security a significant challenge. In this context, a multidimensional food security analysis can provide policymakers with the insights needed for timely interventions.
Henock Abate Demessia +2 more
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Opportunity windows accelerate action and expand options for climate adaptation in Europe
Communications Earth & EnvironmentClimate adaptation must be intensified globally to keep up with increasing climate change impacts. To date, adaptation is mostly driven by climate risks that need to be reduced and little by opportunities. We identify opportunity windows -i.e. favourable
Valeria Di Fant +5 more
doaj +1 more source
Remote SensingAccurate and rapid delineation of wildfire-affected areas is essential in the era of climate-driven increases in fire frequency. This study compares and analyzes four techniques for identifying wildfire-affected areas using Sentinel-2 satellite imagery: (
Sang-Hoon Lee +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Project Risk Management Phases [PDF]
Risk management is the human activity which integrates recognition of risk, risk assessment, developing strategies to manage it, and mitigation of risk using managerial resources.
Claudiu-George BOCEAN
core
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
From risk management to ERM [PDF]
At one point in time, there was self-insurance. Then came risk management. Now comes the era of enterprise risk management(ERM). Traditional risk management will always be necessary, but ERM will complement existing risk activities by extending the field
rochette, michel
core +1 more source