Results 51 to 60 of about 2,950,016 (287)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Challenges and Strategies to Promote Social Effects of the Earthquake Rumors [PDF]

مطالعات مدیریت راهبردی, 2016
High seismicity and earthquake occurrence is one of the most important concerns of urban management in Tehran metropolitan. Unfortunately, this is being neglected because of the earthquake nature, human negligence and long-time return period of severe ...
Farokh Parsizadeh, Parvaneh Pishnamazi
doaj  

Evaluation of climate induced hazards risk for coastal Bangladesh: a participatory approach-based assessment

Geomatics, Natural Hazards & Risk, 2021
Bangladesh has been identified as one of the most susceptible countries to climate induced disasters. Geographical location of the country in the foothill of Himalayan system and in the mouth of north Bay of Bengal make it to experience frequent extreme ...
Md Faisal, Milton Kumar Saha, Md Abdus Sattar, A. K. M Abdul Ahad Biswas, Md Afjal Hossain   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Risk-Tex

, 1998
Newsletter published by the Texas State Office of Risk Management discussing news, events, and activities of the agency as well as other topics related to risk management for state employees.
Texas. State Office of Risk Management.
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

An economic assessment of population health risk in region [PDF]

Экономика региона, 2012
This paper proposes a method of economic assessment of population health risk as a tool of life qualitymanagement and qualityof labor resources in the region (as factors of a region’s economic security).
Nina Vladimirovna Zaytseva , Pavel Zalmanovich Shur, Ol’ga Ivanovna Goleva   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Impacts of drought on rural livelihoods an evidence of climate change affected areas of Amhara region in Ethiopia

Discover Sustainability
The study aims to assess the impact of climate change induced drought on the rural livelihoods of households in Beyeda woreda. The study used explanatory research design and mixed research methods. Survey data was collected from 123 households.
Yilebes Addisu Damtie, Birtukan Atinkut Asmare, Tilahun Ambelu, Henock Abate Demessia, Emiamrew Yoseph G/egziabher, Yosef Tamiru Seifu   +5 more
doaj   +1 more source

Patterns of mortality risk among patients with substance use disorder: an opportunity for proactive patient safety?

BMC Psychiatry, 2022
Background Patients with substance use disorder (SUD) suffer from excess mortality compared to the overall population. This study aims to identify patterns in death rates among patients with SUD visiting a SUD emergency ward and to explore whether this ...
Jakob Svensson, Johan Bergström, Martin Kåberg, Per Becker   +3 more
doaj   +1 more source