Results 61 to 70 of about 2,950,016 (287)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Positive Communication Reduces Risk and Improves Dental Patient Outcomes

open access: yesJournal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Navigating AwDa Compliance: Providing Inclusive Care for Patients with Special Needs

open access: yesJournal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Risks and Risk Management in Agriculture

open access: yesZeszyty Naukowe SGGW w Warszawie - Problemy Rolnictwa Światowego, 2013
Agriculture has always been exposed to a wide spectrum of risks. But it is largely undisputed that farmers have faced growing risks in recent years. More volatile agricultural and input prices, climate change, ongoing discussions about the future of the Common Agricultural Policy, increasing difficulty in finding qualified farm workers, and growing ...
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Haste, Pressure and Staffing Shortages Contribute to Costly Mistakes

open access: yesJournal of the California Dental Association, 2023
TDIC Risk Management Staff
doaj   +1 more source

Disaster-induced displacement in the Caribbean and the Pacific

open access: yesForced Migration Review, 2017
People in Small Island Developing States are particularly vulnerable to displacement by disaster. Governments in the Caribbean and the Pacific need urgently to do more risk management and planning, rather than focusing almost exclusively on response and ...
Mo Hamza, Ida Koch, Malte Plewa
doaj  

Leveraging Bayesian Quadrature for Accurate and Fast Credit Valuation Adjustment Calculations

open access: yesMathematics
Counterparty risk, which combines market and credit risks, gained prominence after the 2008 financial crisis due to its complexity and systemic implications.
Noureddine Lehdili   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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