Results 61 to 70 of about 2,950,016 (287)
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Positive Communication Reduces Risk and Improves Dental Patient Outcomes
TDIC Risk Management Staff
doaj +1 more source
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Navigating AwDa Compliance: Providing Inclusive Care for Patients with Special Needs
TDIC Risk Management Staff
doaj +1 more source
Risks and Risk Management in Agriculture
Agriculture has always been exposed to a wide spectrum of risks. But it is largely undisputed that farmers have faced growing risks in recent years. More volatile agricultural and input prices, climate change, ongoing discussions about the future of the Common Agricultural Policy, increasing difficulty in finding qualified farm workers, and growing ...
openaire +2 more sources
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Haste, Pressure and Staffing Shortages Contribute to Costly Mistakes
TDIC Risk Management Staff
doaj +1 more source
Disaster-induced displacement in the Caribbean and the Pacific
People in Small Island Developing States are particularly vulnerable to displacement by disaster. Governments in the Caribbean and the Pacific need urgently to do more risk management and planning, rather than focusing almost exclusively on response and ...
Mo Hamza, Ida Koch, Malte Plewa
doaj
Leveraging Bayesian Quadrature for Accurate and Fast Credit Valuation Adjustment Calculations
Counterparty risk, which combines market and credit risks, gained prominence after the 2008 financial crisis due to its complexity and systemic implications.
Noureddine Lehdili +2 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

