Results 41 to 50 of about 2,263,259 (265)

Regulatory-required post-marketing database studies in Japan could be leveraged to assess important potential risks as well as identified risks

Frontiers in Pharmacology
BackgroundTo investigate the characteristics of post-marketing database studies (PMDS) included in risk management plans (RMPs) across all therapeutic areas in Japan.MethodsTwo researchers systematically and independently reviewed all RMPs listed on the ...
Hiroshi Yamazaki, Ko Nakajo, Naoki Hirose, Li Yan, Sun Yeop Lee, Yongjing Zhang, Hong Qiu, Chieko Ishiguro   +7 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Current situation and issues regarding termination of risk management plans in Japan

Frontiers in Medicine
IntroductionIn Japan, drugs approved after the 2013 implementation of the risk management plan (RMP) have the opportunity to be evaluated for RMP termination. However, the guidelines for risk management following the termination of an RMP remain unclear.
Natsuko Kameyama, Aoi Hosaka, Hideki Maeda, Hideki Maeda   +3 more
doaj   +1 more source

Hierarchical Risk Communication Management Framework for Construction Projects

Engineering Management in Production and Services, 2023
Risk, as an effect of uncertainty, is associated with every human activity. Like any other industry, construction companies are eager to reduce the uncertainty of reluctant events.
Mansour Mohammad A., Beithou Nabil, Alsqour Moh’d, Tarawneh Sultan A., Rababa’a Khalid Al, AlSaqoor Sameh, Chodakowska Ewa   +6 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Process-based project proposal risk management [PDF]

Trendy v podnikání, 2016
We all are aware of the organizational omnipresence. Projects within the organizations are ubiquitous too. Projects achieve their goals successfully if they are planned, scheduled, controlled and implemented well.
Alok Kumar
doaj  

Disaster Risk Reduction Based on Community through a Contingency Plan for Mount Sinabung

JSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2018
The eruption of Mount Sinabung in Karo district of North Sumatera has continued on and off since 2010. A contingency plan is needed to reduce the risk of disaster.
Puji Lestari, Eko Teguh Paripurno, Arif Rianto Budi Nugroho   +2 more
doaj   +1 more source

A construction–specific extension to a standard project risk management process

Organization, Technology and Management in Construction: An International Journal, 2022
Project processes are affected by risks in many ways, and this is particularly true in today's highly competitive world. Construction projects usually take much longer than typical projects in other sectors. In this sector, it is important to follow some
Alfreahat Dina, Sebestyén Zoltán
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Protective strategies and management recommendations for medical staff based on NIOSH's Managing Hazardous Drug Exposures: Information for Healthcare Settings (2023 Edition)

环境与职业医学
The Hazardous Drug Exposure Management: Information for Healthcare Settings (2023 Edition) released by the National Institute for Occupational Safety and Health (NIOSH) of US provided detailed protection recommendations for medical personnel to mitigate ...
Hengjuan LIANG, Bo YANG, Jing WEN, Xiaohong HUANG   +3 more
doaj   +1 more source