Results 81 to 90 of about 2,263,259 (265)

The application of holistic risk management in the banking industry

open access: yesActa Commercii, 2007
Purpose: The application of holistic risk management is fast becoming a standard measure of good governance in the business arena. What role can holistic risk management play in the management of risk in the financial services industry?
J. Chibayambuya, D. J. Theron
doaj   +1 more source

Model-Based Mitigation of Availability Risks [PDF]

open access: yes, 2007
The assessment and mitigation of risks related to the availability of the IT infrastructure is becoming increasingly important in modern organizations. Unfortunately, present standards for Risk Assessment and Mitigation show limitations when evaluating ...
Bolzoni, Damiano   +3 more
core   +7 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Optimal Coverage Level Choice with Individual and Area Plans of Insurance [PDF]

open access: yes
We theoretically examine a farmer’s coverage demand with area and individual insurance plans as either separate or integrated options. The individual and area losses are assumed to be imperfectly and positively correlated.
Bulut, Harun   +2 more
core   +4 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Risk Management Plan [PDF]

open access: yes, 2001
The purpose of this Risk Management Plan (RMP) is to establish the concept and define the process to assure that National Nuclear Security Administration Nevada Operations Office Environmental Management (NNSA/NV EM) programs and projects incorporate appropriate, efficient, cost-effective measures to mitigate the impact of program-and/or project ...
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The risk management system as the important part of good pharmacovigilance practices (GVP)

open access: yesБезопасность и риск фармакотерапии, 2018
The risk management system includes the process of determining the probability of occurrence of undesirable effects of pharmacotherapy, identifying the extent and magnitude of the risk analysis and the choice of risk management strategy, the selection of
A. S. Kazakov   +4 more
doaj  

Critical success factors in ERP implementation: A review [PDF]

open access: yes, 2008
ERP systems have become vital strategic tools in today’s competitive business environment. This ongoing research study presents a review of recent research work in ERP systems.
Al-Fawaz, K, Al-Salti, Z, Eldabi, T
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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