Results 81 to 90 of about 29,683,568 (291)

Risk-Tex [PDF]

open access: yes, 1999
Newsletter published by the Texas State Office of Risk Management discussing news, events, and activities of the agency as well as other topics related to risk management for state employees.
Texas. State Office of Risk Management.
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Assessment of a New Cloud Fraction Scheme for Precipitation Simulations Over the Tibetan Plateau

open access: yesAdvances in Meteorology
Accurate precipitation simulation over the Tibetan Plateau (TP) remains a major challenge for numerical weather forecasting due to the region’s complex terrain and highly heterogeneous convective processes.
Boyu Liao, Shuzhou Wang
doaj   +1 more source

Simultaneous Remote Sensing of HD16O/H216O Profile Using Differential Absorption Lidar: A Feasibility Analysis

open access: yesRemote Sensing
A novel multi-wavelength differential absorption lidar operating at 1.5 μm band is proposed and theoretically analyzed for simultaneous remote sensing of vertical profiles of H216O, HD16O, and the isotopic ratio δD.
Saifen Yu, Zhen Zhang, Haiyun Xia
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Probabilistic Forecasting Model for Tropical Cyclone Intensity Based on Diffusion Model

open access: yesRemote Sensing
Reliable forecasting of tropical cyclone (TC) intensity—particularly rapid intensification (RI) events—remains a major challenge in meteorology, largely due to the inherent difficulty of accurately quantifying predictive uncertainty.
Jingjia Luo, Peng Yang, Fan Meng
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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