Results 91 to 100 of about 2,894,776 (300)
Understanding the Internal Measurement Approach to Assessing Operational Risk Capital [PDF]
The recent publication by the Basel Committee of CP2.5, the working paper on Operational Risk Capital Charges, has shed new light on the methods that will be proposed for the measurement of operational risks in the Basel II Accord.
Carol Alexander
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
CONTINGENCIES FOR MEASUREMENT OF THE CREDIT RISK [PDF]
Buletin ştiinţific: Universitatea din Piteşti. Seria Ştiinţe Economice, 2015 The Global Financial Crisis, which affected various banks, some of them very important banks, highlighted the importance of an accurate credit risk measurement in order to be able to overcome it. There are a variety of such credit risk measurement models,
Marinela BARBULESCU +2 more
doaj
Imaging Breast Density: Established and Emerging Modalities
Translational Oncology, 2015 Mammographic density has been proven as an independent risk factor for breast cancer. Women with dense breast tissue visible on a mammogram have a much higher cancer risk than women with little density.
Jeon-Hor Chen +2 more
doaj +1 more source
Measurement of Farm Credit Risk: SUR Model and Simulation Approach [PDF]
The study addresses problems in measuring credit risk under the structure model, and then proposes a seemingly unrelated regression model (SUR) to predict farms’ ability in meeting their current and anticipated obligations in the next 12 months.
Barry, Peter J. +3 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
مجله انفورماتیک سلامت و زیست پزشکی, 2018 Introduction: Brucellosis is one of the most common zoonotic infections, which is considered as a potential public health threat. Geographical information system (GIS) can be a great help to managers and policy makers in the public health field for ...
payman Abbasi +2 more
doaj
Measurement properties of the Sexual Risk Behaviors Scale (SRBS) in university students in Brazil [PDF]
Einstein (São Paulo)Objective This study aimed to translate and evaluate the measurement properties of the Sexual Risk Behaviors Scale into Brazilian Portuguese for use in university students.
Jainé Dalmolin +6 more
doaj +2 more sources
, 2010 PURPOSE: The aim of this study was to examine the relation of late-stage age-related macular degeneration (AMD) with markers of systemic atherothrombosis. METHODS: A hospital-based case-control study of AMD was undertaken in London, UK.
A R Rudnicka +59 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source