Results 121 to 130 of about 2,894,776 (300)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Asset and Liabilities Management. The Institutional Approach to ALM by Commercial Banks in Poland: a Special Focus on Risk Management [PDF]
According to the early evidence, privatization and consolidation of banks have a strong favorable impact on the advancement of ALM and risk management methods. This paper examines various approaches to ALM by commercial banks in Poland.
Katarzyna Zawalinska
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Comparison of GARCH Model and Monte Carlo Simulation for Estimating the Value at Risk of Foreign Exchange Portfolio [PDF]
پژوهشهای اقتصادی, 2011 One of the key concepts in risk managing of financial portfolios is the probability based risk measurement method known as value at risk. During recent years, various methods have been introduced by researchers to compute this criterion. Because of their
Zahra Nasrollahi +2 more
doaj
Do Transaction Costs and Risk Preferences Influence Marketing Arrangements in the Illinois Hog Industry? [PDF]
Studies of hog industry structure often invoke risk reduction and transaction costs explanations for empirical observations but fail to directly examine the core concepts of risk behavior and transaction costs theories.
Franken, Jason R.V. +2 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Operational Risk in the Outlook of the Basel II Accord Implementation [PDF]
Theoretical and Applied Economics, 2007 The financial scandals în the last two decades have determined the Basel Committee to improve the risk controls for banks în general, and for operational risk in particular.
Andrei Tinca
doaj
Financial Risk Measurement for Financial Risk Management [PDF]
Current practice largely follows restrictive approaches to market risk measurement, such as historical simulation or RiskMetrics. In contrast, we propose flexible methods that exploit recent developments in financial econometrics and are likely to ...
Francis X. Diebold +3 more
core
Stock Market Risk Measurement Method Based on Improved Genetic Algorithm
Chemical Engineering Transactions, 2016 In this paper, we concentrate on the problem of stock market risk measurement, which is of great importance for the healthy development of the stock market. The main innovations of this paper lie in that 1) we introduce the GARCH model in stock market risk measuring, and 2) we utilize the Value-at-Risk (VaR) as the stock market risk measure.
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source