Results 111 to 120 of about 10,022,624 (305)

Stock price prediction portfolio optimization using different risk measures on application of genetic algorithm for machine learning regression [PDF]

Accounting
This research aims to enhance portfolio selection by integrating machine learning regression algorithms for predicting stock returns with various risk measures.
Amir Hossein Gandomi, Seyed Jafar Sadjadi, Babak Amiri   +2 more
doaj   +1 more source

Risk Measure Analysis

IEEE Access
Assessing the financial risks is an essential component of portfolio management. This assessment involves the employment of one or more risk measures, i.e., quantitative coefficients employed to capture how risky a portfolio is. As the risk measures are important both to create and evaluate portfolios, it is imperative to understand their ...
Adriano Chaves Lisboa, Felipe Augusto Cardoso Pereira, Fellipe Fernandes Goulart Dos Santos, Lidia Caroline A. Pereira Da Silva, Airton Isaac Pereira, Matheus de Oliveira Mendonça, Gustavo Rodrigues Lacerda Silva, Lais Claudine Schiavo Gomes, Douglas Alexandre Gomes Vieira   +8 more
openaire   +3 more sources

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Multiobjective Lagrangian duality for portfolio optimization with risk measures [PDF]

In this paper we present an application for a multiobjective optimization problem. The objective functions of the primal problem are the risk and the expected pain associated to a portfolio vector. Then, we present a Lagrangian dual problem for it.
Elisa Pagani
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Paradoxical Associations of Occupational and Nonoccupational Sedentary Behavior With Cardiovascular Disease Risk Measures in Desk Workers. [PDF]

J Occup Environ Med, 2023
Alansare AB, Paley JL, Quinn TD, Gibbs BB.   +3 more
europepmc   +1 more source

Solvency capital, risk measures and comonotonicity: a review. [PDF]

In this paper we examine and summarize properties of several well-known risk measures that can be used in the framework of setting solvency capital requirements for a risky business.
Kaas, R, Goovaerts, Marc, Dhaene, Jan, Tang, Q, Vanduffel, Steven, Vyncke, David   +5 more
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

CAPM and APT-like models with risk measures. [PDF]

The paper deals with optimal portfolio choice problems when risk levels are given by coherent risk mea sures, expectation bounded risk measures or general deviations. Both static and dynamic pricing models may be involved.
Balbás, Alejandro, Balbás, Raquel, Balbás, Beatriz   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source