Results 91 to 100 of about 5,312,301 (290)
Risk measures, measures for insolvency risk and economical capital allocation. [PDF]
In the present paper we consider several measures for the risk that is present in an insurance environment. We look for desirable properties for two types of risk measures, the ones reflecting both negative and positive results, and the measures for ...
Dhaene, Jan +2 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Risk Adjusted Productivity Measures [PDF]
Risk, Productivity measures, DEA, Hyperbolic distance function, Panel data, Productivity Analysis, Research Methods/ Statistical Methods, Risk and Uncertainty,
Glazyrina, Anna, Shaik, Saleem
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Exponential Spectral Risk Measures [PDF]
Spectral risk measures are attractive risk measures as they allow the user to obtain risk measures that reflect their subjective risk-aversion. This paper examines spectral risk measures based on an exponential utility function, and finds that these risk
Cotter, John, Dowd, Kevin
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Innovar: Revista de Ciencias Administrativas y Sociales, 2010 An accurate estimation of extreme claims is fundamental to assess solvency capital requirements (SCR) established by Solvency II. Basing on the Extreme Value Theory (EVT), this paper performs a parametric estimation to fit the motor liability insurance ...
María José Pérez-Fructuoso +1 more
doaj
A Novel Approach for Naive Diversification: An Application of Multiple Risk Measures to Enhance 1/N Portfolio Performance [PDF]
International Journal of Management, Accounting and EconomicsThe 1/N investment strategy, characterized by equally allocating wealth among available investment options, has garnered significant scholarly attention.
Mostafa Shabani +3 more
doaj +1 more source
Measures of downside risk [PDF]
The paper characterizes a family of downside risk measures. They depend on a target value and a parameter reflecting the attitude towards downside risk. The indicators are probability weighted -order means of possible shortfalls.
Udo Ebert
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source