Results 81 to 90 of about 10,022,624 (305)
Optimization of Risk Measures [PDF]
We consider optimization problems involving coherent risk measures. We derive necessary and sufficient conditions of optimality for these problems, and we discuss the nature of the nonanticipativity constraints.
Andrzej Ruszczynski, Alexander Shapiro
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
PERFORMANCE LOSS QUANTIFICATION IN KERNEL DENSITY ESTIMATION FOR ACTUARIAL AND FINANCIAL ANALYSIS
Accurately estimating aggregate loss distributions is critical in actuarial and financial risk assessment, as it underpins effective risk analysis and the development of mitigation strategies.
Shafira Fauzia Untsa +3 more
doaj +1 more source
Measures of downside risk [PDF]
The paper characterizes a family of downside risk measures. They depend on a target value and a parameter reflecting the attitude towards downside risk. The indicators are probability weighted -order means of possible shortfalls.
Udo Ebert
core
On representing claims for coherent risk measures [PDF]
We consider the problem of representing claims for coherent risk measures. For this purpose we introduce the concept of (weak and strong) time-consistency with respect to a portfolio of assets, generalizing the one defined in Delbaen [7]. In a similar
Berkaoui, Abdelkarem, Jacka, Saul D.
core
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A risk-return association under normal market conditions can be conventional positive (risk-averse) or “paradoxical„ negative (risk seeking).
Ranjan Das Gupta, Rajesh Pathak
doaj +1 more source
A representation of risk measures [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Conditional and Dynamic Convex Risk Measures [PDF]
We extend the definition of a convex risk measure to a conditional framework where additional information is available. We characterize these risk measures through the associated acceptance sets and prove a representation result in terms of conditional ...
Kai Detlefsen, Giacomo Scandolo
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

