Results 171 to 180 of about 10,022,624 (305)

Infant limb kinematics and muscle force variation during kicking is associated with clinical cerebral palsy risk measures. [PDF]

PLoS One
Khatib NS, Schmidtke LJ, Lukens A, Arichi T, Muceli S, Burdet E, Kainz B, Nowlan NC.   +7 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Circadian gene expression in adolescents: Associations with concurrent circadian disruption and subsequent changes in cardiometabolic risk measures. [PDF]

Sleep Med
Su D, Goodrich JM, Lee JT, Dolinoy DC, Peterson KE, Chervin RD, Burgess HJ, Téllez-Rojo MM, Cantoral A, Torres-Olascoaga L, Tolentino M, Song PXK, O'Brien LM, Jansen EC.   +13 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Comparison of associations of intake of ultra-processed and non-ultra-processed whole-grain foods with cardiometabolic risk measures in Australian and US adults. [PDF]

Eur J Nutr
Price EJ, Du M, Barrett EM, McKeown NM, Batterham MJ, Zhang FF, Martínez-Steele E, Beck EJ.   +7 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Beyond the modified Frailty Index-5: Toward superior frailty risk measures. [PDF]

Shoulder Elbow
Sabet C, Jain B, Abbasian H, Franco J.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The decision uncertainty toolkit: Risk measures and visual outputs to support decision making during public health crises. [PDF]

PLoS One
Wiggins M, Varughese M, Rafferty E, van Katwyk S, McCabe C, Round J, Kirwin E.   +6 more
europepmc   +1 more source

Divergence-Based Risk Measures: A Discussion on Sensitivities and Extensions. [PDF]

Entropy (Basel), 2019
Xu M, Angulo JM.
europepmc   +1 more source