Results 31 to 40 of about 7,974,169 (304)

Global Variability and Future Projections of Marine Heatwave Onset and Decline Rates

Remote Sensing
Marine heatwaves (MHWs) can significantly impact marine ecosystems and socio-economic systems, and their severity may increase with global warming. Nevertheless, research on the onset and decline rates of MHWs remains limited, and their historical and ...
Yongyan Pan, Wenjin Sun, Senliang Bao, Mingshen Xie, Lei Jiang, Jinlin Ji, Yang Yu, Changming Dong   +7 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Pseudo-bifurcations in stochastic non-normal systems and the limits of early-warning signals

Communications Physics
Early-warning indicators in ecosystems, neural activity, financial markets, and climate systems are often interpreted as evidence that a system is approaching a tipping point, typically understood as a bifurcation at which a previously stable state loses
Virgile Troude, Sandro Claudio Lera, Ke Wu, Didier Sornette   +3 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

A high-precision catalogue of landslide events in China based on news text mining with large language model

Scientific Data
Landslides are a major geological hazard causing significant casualties and economic losses. Reliable risk assessment requires high-quality spatiotemporal event data, yet no publicly available landslide catalogue with fine-grained precision exists for ...
Binru Zhao, Lulu Zhang, Zhenxia Liu, Wenchao Ma, Jian Wang, Qiang Sun, Wen Luo, Zhaoyuan Yu, Linwang Yuan   +8 more
doaj   +1 more source

Evaluation of Urban Street Historical Appearance Integrity Based on Street View Images and Transfer Learning

ISPRS International Journal of Geo-Information
The challenges of globalization and urbanization increasingly impact the Historic Urban Landscape (HUL), yet fine-grained and quantitative methods for evaluating HUL remain limited.
Jiarui Xu, Yunxuan Dai, Jiatong Cai, Haoliang Qian, Zimu Peng, Teng Zhong   +5 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Predicting Risk with Risk Measures: An Empirical Study [PDF]

SSRN Electronic Journal, 2018
In this study we consider the risk estimation as a stochastic process based on the Sample Quantile Process (SQP) - which is a generalization of the Value-at-Risk calculated on a rolling sample. Using SQP's, we are able to show and quantify the pro-cyclicality of the current way financial institutions measure their risk.
Bräutigam, Marcel, Dacorogna, Michel, Kratz, Marie   +2 more
openaire   +2 more sources

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Breast Cancer Risks and Risk Prediction Models [PDF]

Breast Care, 2015
<i>BRCA1/2</i> mutation carriers have a considerably increased risk to develop breast and ovarian cancer. The personalized clinical management of carriers and other at-risk individuals depends on precise knowledge of the cancer risks. In this report, we give an overview of the present literature on empirical cancer risks, and we describe ...
Christoph, Engel, Christine, Fischer
openaire   +2 more sources