Results 91 to 100 of about 9,469,034 (350)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Research on the risk contagion of banks holding subordinated debt from the perspective of risk preferences

Frontiers in Physics
IntroductionUnder global integration, banking system stability is paramount for financial market stability. While subordinated debt enhances bank capital stability, it poses capital loss risks to creditor banks upon issuer bankruptcy. This paper examines
Shuting Chen, Shanshan Jiang, Yikang Zhuang, Lingyi Meng   +3 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Profit allocation method of coalition including multi-energy based on Nash-Harsanyi game theory

Diance yu yibiao
Energy resources belonging to independent owners under the background of multi-energy coalition participating in the market, thus ensuring the fairness of the profit allocation of each player becomes crucial.
LIU Zeyuan, LIU Junyong, LIU Jichun, TANG Zhiyuan, ZHANG Hong   +4 more
doaj   +1 more source

From risk behavior to perceived farm resilience: a Dutch case study

Ecology and Society, 2020
In an era where farmers face considerable levels of intertwined risks and uncertainties, farm resilience is developing into a focal point for agricultural policies.
Thomas Slijper, Yann de Mey, P. Marijn Poortvliet, Miranda P. M. Meuwissen   +3 more
doaj   +1 more source

Alcohol demand and risk preference [PDF]

Journal of Economic Psychology, 2008
Both economists and psychologists have studied the concept of risk preference. Economists categorize individuals as more or less risk-tolerant based on the marginal utility of income. Psychologists categorize individuals' propensity towards risk based on harm avoidance, novelty seeking and reward dependence traits. The two concepts of risk are related,
Dhaval, Dave, Henry, Saffer
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

At risk of being risky: The relationship between "brain age" under emotional states and risk preference. [PDF]

, 2017
Developmental differences regarding decision making are often reported in the absence of emotional stimuli and without context, failing to explain why some individuals are more likely to have a greater inclination toward risk.
Bonnie, Richard J, Breiner, Kaitlyn, Casey, BJ, Chein, Jason, Cohen, Alexandra O, Dellarco, Danielle V, Fair, Damien A, Fettich, Karla C, Galván, Adriana, Miranda-Domínguez, Oscar, Richeson, Jennifer A, Rudolph, Marc D, Scott, Elizabeth S, Steinberg, Laurence, Taylor-Thompson, Kim   +14 more
core   +2 more sources

Neural Correlates of Anticipation Risk Reflect Risk Preferences [PDF]

The Journal of Neuroscience, 2012
Individual risk preferences have a large influence on decisions, such as financial investments, career and health choices, or gambling. Decision making under risk has been studied both behaviorally and on a neural level. It remains unclear, however, how risk attitudes are encoded and integrated with choice. Here, we investigate how risk preferences are
Rudorf, Sarah, Preuschoff, Kerstin, Weber, Bernd   +2 more
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source