Results 51 to 60 of about 459,973 (296)

Assessing the environmental risks of sulfonylurea pollutants: Insights into the risk priority and structure-toxicity relationships

Ecotoxicology and Environmental Safety
Sulfonylureas are widely used herbicides globally; however, the health risks associated with exposure to these compounds are poorly understood. This study used fuzzy clustering to categorize 44 sulfonylurea compounds into three risk priority levels (I ...
Zhi-Cong He, Tao Zhang, Xin-Fang Lu, Rui Li, Wei Peng, Fei Ding   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Risk Evaluation in Failure Mode and Effects Analysis Based on D Numbers Theory

International Journal of Computers Communications & Control, 2019
Failure mode and effects analysis (FMEA) is a useful technology for identifying the potential faults or errors in system, and simultaneously preventing them from occurring. In FMEA, risk evaluation is a vital procedure.
B. Liu, Yong Deng
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Queue Length Asymptotics for Generalized Max-Weight Scheduling in the presence of Heavy-Tailed Traffic [PDF]

, 2010
We investigate the asymptotic behavior of the steady-state queue length distribution under generalized max-weight scheduling in the presence of heavy-tailed traffic. We consider a system consisting of two parallel queues, served by a single server.
Jagannathan, Krishna, Markakis, Mihalis, Modiano, Eytan, Tsitsiklis, John N.   +3 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Development of a risk score for colorectal cancer in Chinese males: A prospective cohort study

Cancer Medicine, 2020
To build a simple predictive model as a guide to stratify average‐risk population for colonoscopy examinations. We collected data from 92 923 males without a prior history of cancer enrolled in the Kailuan Cohort Study of China.
Lanwei Guo, Hongda Chen, Gang Wang, Zhangyan Lyu, Xiaoshuang Feng, Luopei Wei, Xin Li, Yan Wen, Ming Lu, Yuheng Chen, Jufang Shi, Jiansong Ren, Chunqing Lin, Xinyang Yu, Shuohua Chen, Shouling Wu, Ni Li, Min Dai, Jie He   +18 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Advancing sustainable shipbuilding through a hybrid risk prioritization model: integrating FMEA and machine learning

Engineering Science and Technology, an International Journal
Effective risk management is critical in modern shipbuilding, where production complexity continues to grow. Traditional Failure Modes and Effects Analysis (FMEA), despite its widespread use, often lacks objectivity and scalability. This study introduces
Ahmet Fatih Yılmaz, Ozan Köse
doaj   +1 more source

Health Risk Map related to Particulate Matter Exposure in Chiang Mai, Thailand

Chemical Engineering Transactions, 2021
Ambient Particulate Matter; PM2.5, with an aerodynamic diameter smaller than or equal to 2.5 µm, has emerged as the most critical health hazard concerning air pollution.
Kannika Jarernwong, Shabbir H. Gheewala, Sate Sampattagul   +2 more
doaj   +1 more source