Results 51 to 60 of about 14,268,135 (288)
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
This study analyses the risk of tofu production at the Saudara Jaya Tofu Factory using the Failure Mode and Effect Analysis (FMEA) method with the aim of identifying potential failures and calculating the Risk Priority Number (RPN) value based on ...
Sindi Putri Sahari, Dhanang Eka Putra
doaj +1 more source
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
In order to secure the safe operation of the ship, it is crucial to closely examine the suitability from the design stage of the ship, and to set up a preliminary review and countermeasures for failures and defects that may occur during the construction ...
Hyeonmin Jeon, Kido Park, Jongsu Kim
doaj +1 more source
Using global positioning system for bus priority in London: traffic signals close to bus stops
London's bus network is one of the largest and most comprehensive urban transport systems in the world. The contribution of buses is recognised by implementing a series of initiatives including bus priority at traffic signals.
Head, J. R. +9 more
core +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Probability Distribution of Risk Priority Numbers in Failure Mode and Effects Analysis
ABSTRACT This study introduces a new probability model for the risk priority number (RPN) in Failure Mode and Effects Analysis (FMEA), addressing limitations of the traditional RPN calculation, which assumes independence among severity, occurrence, and detection scores.
Mahmoudvand, Rahim +3 more
openaire +3 more sources
Characteristics of failure and risk priority number (Process: Assessment of disease).
Characteristics of failure and risk priority number (Process: Assessment of disease).
Koji Wada (259162) +3 more
core +1 more source

