Results 71 to 80 of about 351,543 (287)

Probability Distribution of Risk Priority Numbers in Failure Mode and Effects Analysis

open access: yesRisk Analysis
ABSTRACT This study introduces a new probability model for the risk priority number (RPN) in Failure Mode and Effects Analysis (FMEA), addressing limitations of the traditional RPN calculation, which assumes independence among severity, occurrence, and detection scores.
Mahmoudvand, Rahim   +3 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

ANFIS method to enhance FMEA water operation model of Indonesia drinking water distribution system

open access: yesJurnal Ilmiah SINERGI
Many problems are found in water treatment and distribution in water operations. Those problems range from low to critical risk. All critical risks must be addressed immediately.
Diah Septiyana   +6 more
doaj   +1 more source

Monte Carlo methods for the estimation of value-at-risk and related risk measures

open access: yes, 2011
Nested Monte Carlo is a computationally expensive exercise. The main contributions we present in this thesis are the formulation of efficient algorithms to perform nested Monte Carlo for the estimation of Value-at-Risk and Expected-Tail-Loss.
Marks, Dean
core  

Beyond Technical Failure: Introducing PRPN — The Pattern-Adjusted Risk Priority Number for Human-Aware Risk Management

open access: yes
Between 60 and 80 percent of significant organisational failures trace their root causes to human behaviour rather than technical malfunction. Yet Failure Mode and Effects Analysis (FMEA) — the dominant structured risk assessment methodology across ...
Shoukathali O P
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Failure Mode and Effects Analysis (FMEA) for Photovoltaic Inverter

open access: yesIEEE Open Journal of Power Electronics
Photovoltaic (PV) inverters are critical yet vulnerable components in modern energy systems, often acting as reliability bottlenecks that increase the levelized cost of energy (LCOE).
Buck F. Brown   +4 more
doaj   +1 more source

A Novel Failure Mode and Effects Analysis Method Based on Fuzzy Evidential Reasoning Rules

open access: yesIEEE Access, 2019
Failure mode and effects analysis (FMEA) is an effective reliability analysis technique and has been used for safety and dependability analysis in a wide range of fields. In the traditional FMEA, a method called risk priority number (RPN) has been widely
Wen Jiang, Zhipeng Zhang, Xinyang Deng
doaj   +1 more source

Bridging the Translation Gap: From Dementia Risk Assessment to Advice on Risk Reduction

open access: yes, 2015
Dementia risk reduction is a global health and fiscal priority given the current lack of effective treatments and the projected increased number of dementia cases due to population ageing.
Hosking, DE   +4 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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