Results 91 to 100 of about 351,543 (287)

A New Failure Mode and Effects Analysis Method Based on Dempster–Shafer Theory by Integrating Evidential Network

open access: yesIEEE Access, 2019
Failure mode and effects analysis (FMEA) is one of the most effective pre-accident prevention methods. Risk priority number (RPN) approach is a traditional method in the FMEA for risk evaluation.
Hongfei Wang   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Reliability Analysis of Wide-Detector CT Equipment Based on Improved FMEA

open access: yesZhongguo yiliao qixie zazhi
ObjectiveAn improved failure mode and effects analysis (FMEA) model is constructed to enhance the accuracy of reliability assessment for wide-detector computed tomography equipment. MethodsA multidisciplinary expert panel is established. A scoring system
Wenhao XU, Wei JIN, Shundong HU
doaj   +1 more source

Failure Mode and Effects Analysis and Risk Priority Number in a Combined Cycle Power Plant

open access: yesArchives of Occupational Health, 2021
Background: Work-related accidents are one of the most important factors in the loss of human lives. With technology and industrial progress, the consequences of accidents due to hazards become more severe and may even stop the work of power plants. This
Elnaz Rahimi   +5 more
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Evaluation of the risk of occupational exposure to antineoplastic drugs in healthcare sector: part II – the application of the FMECA method to compare manual vs automated preparation

open access: yesArhiv za Higijenu Rada i Toksikologiju
Healthcare workers handling antineoplastic drugs (ADs) in preparation units run the risk of occupational exposure to contaminated surfaces and associated mutagenic, teratogenic, and oncogenic effects of those drugs.
Dugheri Stefano   +9 more
doaj   +1 more source

Credit Enhancement through Financial Engineering: Freeport-McMoRan's Gold-Denominated Depository Shares [PDF]

open access: yes
In 1993 and early 1994, Freeport McMoRan Copper and Gold (FCX), a mining company, issued two series of gold-denominated depositary shares to raise 430 million dollars expanding their mining capacity in Indonesia.
N. K. Chidambaran   +2 more
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

ANALISIS KECELAKAAN KERJA DENGAN MENGGUNAKAN METODE RISK PRIORITY NUMBER, DIAGRAM PARETO, FISHBONE, FIVE WHYS ANALYSIS

open access: yes, 2021
Keselamatan dan kesehatan kerja merupakan salah satu faktor penting dalam kelancaran produksi sehingga program K3 harus diterapkan di perusahaan dan bukan hanya sekedar wacana.
Rohani, Qonita Aulia   +1 more
core  

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