Results 111 to 120 of about 351,543 (287)

ASSESSMENT OF RISK USING RISK PRIORITY NUMBER AND FUNCTIONAL PRIORITY NUMBER FOR BRIDGES

International Research Journal of Modernization in Engineering Technology and Science, 2023
openaire   +1 more source

The Role of Guarantees in Bank Lending. [PDF]

Guarantees play an important role in debt contracts. They alter the risk for the lender, transform borrowers' incentives and, possibly, modify the equilibrium allocation of financial resources.
Pozzolo, Alberto Franco
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Failure mode identification and effects analysis of mobile X-ray machine using selected MADM techniques

Scientific Reports
Failure mode and effects analysis (FMEA) is a method of reliability analysis that healthcare organizations employ to increase the reliability and safety of their services and products.
Vikas Sisodia, Dharmalingam Ganesan, Sachin Salunkhe, Robert Čep, Emad Abouel Nasr   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Failure Mode and Effects Analysis By using Robust Data Envelopment Analysis [PDF]

Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2015
Improving products quality and services is the best and most important factor to win competitors and get majority of the market share. In this regard, Failue mode and Effect analysis is an efficient tool to improve the quality products.
Alireza Alinezhad, Niki Jalili Taghavian
doaj  

Australian wildland-urban interface householders’ wildfire safety preparations: ‘Everyday life’ project priorities and perceptions of wildfire risk

, 2019
Globally, many residents of wildland-urban interface (WUI) communities are at risk of wildfire attack but do not undertake adequate preparations.
K Koksal (9867992), Danielle Every (9795050), Christopher Bearman (9780020), Koksal, Kubra, Christopher Bearman, J McLennan (9866186), Bearman, Christopher, Kubra Koksal, McLennan, Jim, Every, Danielle S, Jim McLennan, Danielle Every   +11 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Should Derivatives be Privileged in Bankruptcy? [PDF]

Derivative contracts, swaps, and repos enjoy "super-senior" status in bankruptcy: they are exempt from the automatic stay on debt and collateral collection that applies to virtually all other claims.
Patrick Bolton, Martin Oehmke
core