Results 101 to 110 of about 18,207,286 (255)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

NbO6 octahedra of high-dimensional Nb2O5 boosting H2O2 electrosynthesis for sewage pollutants degradation

Nano Research
Two-electron oxygen reduction reaction (2e− ORR) to produce hydrogen peroxide (H2O2) presents an efficient, secure, and sustainable method. However, the competing four-electron pathway produces H2O, yielding low H2O2 selectivity (~ 70%).
Bingxue Cheng, Xinlin Wang, Shijia Li, Yuhang Li, Toru Murayama, Tamao Ishida, Guangli Xiu, Kenji Iida, Yufan Fu, Yining Wang, Mingyue Lin   +10 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Sociology of Leisure: Risk and Leisure RLO

, 2010
This RLO is part of “Sociology of Leisure” course. The module discusses some major features of current leisure patterns, but these activities are also central to modern life itself and thus have interests for sociologists.
Dr Dave Harris, MARJON
core  

Simultaneous Degradation, Dehalogenation, and Detoxification of Halogenated Antibiotics by Carbon Dioxide Radical Anions

Engineering
Despite the extensive application of advanced oxidation processes (AOPs) in water treatment, the efficiency of AOPs in eliminating various emerging contaminants such as halogenated antibiotics is constrained by a number of factors.
Yanzhou Ding, Xia Yu, Shuguang Lyu, Huajun Zhen, Wentao Zhao, Cheng Peng, Jiaxi Wang, Yiwen Zhu, Chengfei Zhu, Lei Zhou, Qian Sui   +10 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Characteristics of invasive alien plants in different urban areas: the case of Kunshan City, Jiangsu Province, China

Frontiers in Plant Science
As globalization progresses, the threat of invasive alien plants to ecosystems is becoming increasingly prominent, and the negative effects of these plants on human health and socioeconomics are gradually increasing with the development of cities; thus ...
Yubing Liu, Yubing Liu, Yueheng Ren, Yueheng Ren, Hua Zhang, Hua Zhang, Dongdong Qiu, Dongdong Qiu, Yanpeng Zhu, Yanpeng Zhu   +9 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Rhizosphere accelerates breakdown of large biodegradable microplastics in soil

Environmental Science and Ecotechnology
The expanding deployment of biodegradable mulch films in global agriculture aims to mitigate persistent plastic pollution, yet the fate of resulting biodegradable microplastics (BMPs) in soil ecosystems remains poorly characterized.
Kailin Gong, Cheng Peng, Xiaoyi Chen, Li Cai, Wei Zhang   +4 more
doaj   +1 more source

Parisian ruin for the dual risk process in discrete-time. [PDF]

Eur Actuar J, 2018
Palmowski Z, Ramsden L, Papaioannou AD.
europepmc   +1 more source