Results 111 to 120 of about 18,207,286 (255)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Classification of rocky desertification degrees and analysis of driving factors in typical karst regions

Frontiers in Environmental Science
Rocky desertification is a major ecological problem in karst regions, driven by the combined effects of natural conditions and human activities. To investigate its spatiotemporal evolution and driving mechanisms, this study constructed a two-dimensional ...
Meng Liu, Meng Liu, Yanjun Chen, Yanjun Chen, Xiao Guan, Xiao Guan, Qiuming Wang, Qiuming Wang, Libo Pan, Libo Pan   +9 more
doaj   +1 more source

Multidisciplinary in-situ simulation to evaluate a rare but high-risk process at a level 1 trauma centre: the “Mega-Sim” approach [PDF]

Can J Surg, 2018
Bradley NL, Innes K, Dakin C, Sawka A, Lakha N, Hameed SM.   +5 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Harry Weese : humanism and tradition (Process Achitecture No. 11)

, 1979
164hlm.;bib ...
Process Architecture
core  

A machine learning-quantitative microbial risk assessment (ML-QMRA) framework for predicting potential health risks from pathogens in drinking water sources

Biocontaminant
Pathogens in drinking water sources are diverse and pose potential health risks, yet rapid monitoring and risk assessment remain challenging. This study established detection methods for three indicator bacteria and six pathogens, and compared six ...
Bingbing Guo, Jing Wang, Chicheng Yan, Chao Tang, Kun Yin, Lei Jiang, Changzheng Cui   +6 more
doaj   +1 more source

The distribution of some extremum on the risk process whose income depend on the current reserve. [PDF]

Springerplus, 2016
He J, Liu Z, Zhang W.
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Rogue traders versus value-at-risk and expected shortfall

, 2018
We show that, in a Black and Scholes market, value at risk and ex- pected shortfall are irrelevant in limiting traders excessive tail-risk seeking behaviour as modelled via Kahneman and Tversky’s S-shaped utility. To have effective constraints one can
Brigo, D, Armstrong, John
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source