Results 111 to 120 of about 6,437,662 (327)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Robust scheduling of integrated electricity and gas systems: A cost and flexibility assessment

International Journal of Electrical Power & Energy Systems
Gas-fired generators and power-to-gas units support the deployment of variable renewable energy in integrated electricity and gas systems (IEGS) by absorbing the fluctuations in electricity generation and demand.
Behnam Akbari, Giovanni Sansavini
doaj  

Fluoranthene degradation in a persulfate system activated by sulfidated nano zero-valent iron (S-nZVI): performance and mechanisms

Water Science and Technology
Fluoranthene (FLT) has received mounting focus due to its hazardous properties and frequent occurrence in groundwater. In this study, sulfidated nano zero-valent iron (S-nZVI) was selected as an efficient catalyst for activating persulfate (PS) to ...
Ruzhuang Zhang, Yi Zhu, Jiaqi Dong, Zhennan Yao, Guilu Zeng, Xianxian Sheng, Ziqian Xu, Shuguang Lyu   +7 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Comparison of naphthalene degradation by hydrogen peroxide, nano-calcium peroxide, peroxydisulfate, and peroxymonosulfate in the Fe(II)-citric acid catalytic environments

Water Supply
Naphthalene (NAP) was chosen as a target contaminant due to its increasing environmental concern in this work. Using hydrogen peroxide (H2O2), nano-calcium peroxide (nCP), peroxydisulfate (PDS), and peroxymonosulfate (PMS) as oxidants activated by Fe(II)-
Ruzhuang Zhang, Xingbin Fang, Yulong Liu, Ming Li, Guilu Zeng, Ruming Yang, Yiqin Qiu, Shuguang Lyu   +7 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

PCDD/Fs in indoor environments of residential communities around a municipal solid waste incineration plant in East China: Occurrence, sources, and cancer risks

Environment International, 2023
Prolonged exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) can pose several adverse outcomes on human health. However, there is limited information on public health associated with indoor PCDD/F exposure in residential ...
Jun Yu, Hui Li, Yongdi Liu, Chen Wang
doaj  

Environmental Protection Agency Risk Assessment— Process and Toxicologic Pathology [PDF]

, 1997
Marion P. Copley
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source