Results 211 to 220 of about 7,140,788 (341)

Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective. [PDF]

Alzheimers Res Ther
Graafland CH, Bunnik EM, Borroni B, Bouzigues A, Borrego-Écija S, Solje E, Graff C, Rohrer JD, van Swieten JC, Donker Kaat L, Seelaar H.   +10 more
europepmc   +1 more source

Integrating Process Safety and Process Security Risk Management: Practitioner Insights for a Resilience-Oriented Framework

Muhammad Firman Haiqal Mohd Rahim, Genserik Reniers, Ming Yang, Parthiban Siwayanan   +3 more
openalex   +1 more source

Performance Analysis of Fuzzy processor for a Healthcare Application-Diabetic Epilepsy Risk Classifier

, 2017
M. Jothi, N. B. Balamurugan, R. Hari Kumar   +2 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Functional Neuroimaging Reveals Neural Processes Underlying Food Technology Attitudes and Risk Perception

, 2019
Erin S. Beyer, M. LaCour, M. F. Miller, T. H. Davis, J. L. Finck   +4 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A New Unifying Definition of Resilience Adapted to the Developmental Psychopathology of Major Psychiatric Disorders: A Requisite for Progress. [PDF]

Can J Psychiatry
Nadifi Y, Popa IA, Brochu L, Girard G, Maziade M.   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Navigating the Emotional Challenges of Grade School: The Influence of Early Family Strains and a Lack of Parental Responsiveness on Trajectories of Anxiety and Depressive Symptoms. [PDF]

Fam Process
Lopez M, Brock RL, James TD, Nelson JM, Espy KA, Nelson TD.   +5 more
europepmc   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source