Results 121 to 130 of about 1,380,859 (329)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Use of the event tree to assess the risk reduction obtained from rockfall protection devices [PDF]
Natural Hazards and Earth System Sciences, 2008 The paper presents and discusses a procedure for the evaluation of the collective risk that can affect a road subjected to rockfalls, with and without protection measures, by means of the event tree analysis. This tool is useful to show designers whether
D. Peila, C. Guardini
doaj
Identification of the corporate entities in the practice of financial monitoring
Ученые записки Российской академии предпринимательства, 2021 The article discusses the options for the process of identification of the client as a person engaged in financial transactions, methods of identifying beneficial owners, which allows the credit institution to implement measures of due diligence of ...
S. S. Gamonenko
doaj
Stemming the Tide: Strategies to Reduce the Growth and Cut the Cost of the Federal Prison System [PDF]
, 2013 The federal prison population has escalated from under 25,000 inmates in 1980 to over 219,000 today. This growth has come at great expense to taxpayers and other important fiscal priorities.
Julie Samuels +2 more
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Growth Options in General Equilibrium: Some Asset Pricing Implications [PDF]
We develop a general equilibrium model of a production economy which has a risky production technology as well as a growth option to expand the scale of the productive sector of the economy.
Erwan Morellec +2 more
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
, 2010 In Dion, P. (Ed.). Soil biology and agriculture in the tropics. Heidelberg, Germany: Springer Verlag ; Wastewater irrigation is becoming a global phenomenon, as a result of global water scarcity and increased pollution of water sources. While this practice offers many opportunities, human health risks from contaminated soils and crops irrigated with ...
Abaidoo, Robert C. +4 more
openaire +1 more source
Debt restructuring in the euro area: a necessary but manageable evil? [PDF]
There are two possible responses to the Greek debt crisis: 'Plan A', continued official lending, for as long as needed, with possible voluntary private sector involvement, and 'Plan B', coercive pre-emptive or post-default restructuring with significant ...
Zsolt Darvas
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