Results 11 to 20 of about 3,593,757 (358)

Integration of risk factor polygenic risk score with disease polygenic risk score for disease prediction

Communications Biology
Polygenic risk score (PRS) is useful for capturing an individual’s genetic susceptibility. However, previous studies have not fully exploited the potential of the risk factor PRS (RFPRS) for disease prediction.
Hyein Jung, Hae-Un Jung, Eun Ju Baek, Shin Young Kwon, Ji-One Kang, Ji Eun Lim, Bermseok Oh   +6 more
doaj   +3 more sources

Risk Assessment for Heroin Use and Craving Score Using Polygenic Risk Score [PDF]

Journal of Personalized Medicine, 2021
Addiction is characterized by drug-craving, compulsive drug-taking, and relapse, and results from the interaction between multiple genetic and environmental factors. Reward pathways play an important role in mediating drug-seeking and drug-taking behaviors, and relapse.
Chieh-Liang Huang, Ping-Ho Chen, Hsien-Yuan Lane, Ing-Kang Ho, Chia-Min Chung   +4 more
openaire   +2 more sources

Pitfalls in systemic-risk scoring [PDF]

Journal of Financial Intermediation, 2013
Regulatory data used to identify Systemically Important Financial Institutions (SIFIs) have gradually become public since 2014. Exploiting this transparency shock, we show that the scoring methodology implemented by the Basel Committee on Banking Supervision is biased and can create wrong incentives for regulated banks. Using regulatory data for 106 US
Benoît, Sylvain, Hurlin, Christophe, Pérignon, Christophe   +2 more
openaire   +7 more sources

Apgar score and risk of autism [PDF]

European Journal of Epidemiology, 2018
Low Apgar score has been associated with higher risk for several neurological and psychiatric disorders, including cerebral palsy and intellectual disability. Studies of the association between Apgar score and autism spectrum disorder (ASD) have been inconsistent. We aimed to investigate (1) the association between low Apgar score at 5 min and risk for
Erik T. Parner, Mika Gissler, Mady Hornig, Sven Sandin, Sven Sandin, Richard W. Francis, Amirhossein Modabbernia, Helen Leonard, Diana Schendel, Abraham Reichenberg, Michaeline Bresnahan, Raz Gross, Kim W. Carter   +12 more
openaire   +5 more sources

The Identifying Depression Early in Adolescence Risk Stratified Cohort (IDEA-RiSCo): Rationale, Methods, and Baseline Characteristics

Frontiers in Psychiatry, 2021
Background: The characterization of adolescents at high risk for developing depression has traditionally relied on the presence or absence of single risk factors.
Christian Kieling, Christian Kieling, Claudia Buchweitz, Claudia Buchweitz, Arthur Caye, Arthur Caye, Pedro Manfro, Pedro Manfro, Rivka Pereira, Rivka Pereira, Anna Viduani, Anna Viduani, Maurício Anés, Lucas Battel, Lucas Battel, Silvia Benetti, Silvia Benetti, Helen L. Fisher, Helen L. Fisher, Rakesh Karmacharya, Brandon A. Kohrt, Thais Martini, Thais Martini, Sandra Petresco, Sandra Petresco, Jader Piccin, Jader Piccin, Thiago Rocha, Thiago Rocha, Luis Augusto Rohde, Luis Augusto Rohde, Fernanda Rohrsetzer, Fernanda Rohrsetzer, Laila Souza, Laila Souza, Bruna Velazquez, Bruna Velazquez, Annabel Walsh, Leehyun Yoon, Zuzanna Zajkowska, Valentina Zonca, Valentina Zonca, Johnna R. Swartz, Valeria Mondelli, Valeria Mondelli   +44 more
doaj   +1 more source

Construction of Prognostic Risk Prediction Model of Oral Squamous Cell Carcinoma Based on Nine Survival-Associated Metabolic Genes

Frontiers in Physiology, 2021
The aim was to investigate the independent prognostic factors and construct a prognostic risk prediction model to facilitate the formulation of oral squamous cell carcinoma (OSCC) clinical treatment plan.
Zhen-Dong Huang, Zhen-Dong Huang, Yang-Yang Yao, Ting-Yu Chen, Yi-Fan Zhao, Chao Zhang, Yu-Ming Niu, Yu-Ming Niu   +7 more
doaj   +1 more source

Effects of Inflammation on the Immune Microenvironment in Gastric Cancer

Frontiers in Oncology, 2021
BackgroundChronic inflammation and immune cell dysfunction in the tumor microenvironment are key factors in the development and progression of gastric tumors.
Weidan Zhao, Mingqing Liu, Mingyue Zhang, Yachen Wang, Yingli Zhang, Shiji Wang, Nan Zhang   +6 more
doaj   +1 more source

SCORE performance in Central and Eastern Europe and former Soviet Union: MONICA and HAPIEE results [PDF]

, 2013
Aims: The Systematic COronary Risk Evaluation (SCORE) scale assesses 10 year risk of fatal atherosclerotic cardiovascular disease (CVD), based on conventional risk factors.
Bobak, M, Broda, G, Kubinova, R, Malyutina, S, Pajak, A, Pikhart, H, Simonova, G, Skodova, Z, Tamosiunas, A, Vikhireva, O   +9 more
core   +3 more sources

Does the revised cardiac risk index predict cardiac complications following elective lung resection? [PDF]

, 2013
Background: Revised Cardiac Risk Index (RCRI) score and Thoracic Revised Cardiac Risk Index (ThRCRI) score were developed to predict the risks of postoperative major cardiac complications in generic surgical population and thoracic surgery respectively.
A Bobbio, A Brunelli, A Brunelli, A Brunelli, Amy Kerr, Andrea Marshall, AS Detsky, Babu Naidu, CA Polanczyk, CD Parmar, D Amar, DJ Bertges, DW Hosmer, E Lim, Ehab Bishay, HC Fernando, JP Mathew, L Goldman, LA Fleisher, Maninder Kalkat, MK Ferguson, MK Ford, Pala Rajesh, Richard Steyn, Robin Wotton, TH Lee, V Fuster, WD Neary   +27 more
core   +2 more sources

Quantifying the risk of coronary artery disease in a community: The Bambuí Project [PDF]

Arquivos Brasileiros de Cardiologia, 2003
OBJECTIVE: To determine the coronary risk profile in adults and elderly in a community. METHODS: The study comprised a sample of adults (30-59 years, n=547) and the entire elderly population (60-74 years, n=1165) residing in Bambuí town, Brazil.
Sandhi Maria Barreto, Valéria Maria Azeredo Passos, Alisson Renê Aquino Cardoso, Maria Fernanda Lima-Costa   +3 more
doaj   +3 more sources