Results 31 to 40 of about 8,656,301 (259)

Global trajectories of polygenic risk score research: a systematic bibliometric review of precision medicine, equity, and clinical translation

Frontiers in Medicine
IntroductionPolygenic risk scores (PRS) have emerged as a central tool in genomic medicine, enabling risk prediction for common, complex diseases. Despite rapid methodological and clinical advances, concerns remain regarding the structural organization ...
Fouad Bitar, Fouad Bitar, Rana Zareef, Roukoz Abou-Karam, Roukoz Abou-Karam, Georges Nemer, Fadi F. Bitar, Akl C. Fahed, Akl C. Fahed, Akl C. Fahed, Zahi Abdul Sater   +10 more
doaj   +1 more source

Catheter Management and Risk Stratification of Patients With in Inpatient Treatment Due to Acute Epididymitis

Frontiers in Surgery, 2020
Objective: This study aims to evaluate catheter management in acute epididymitis (AE) patients requiring inpatient treatment and risk factors predicting severity of disease.Material and Methods: Patients with diagnosed AE and inpatient treatment between ...
Mike Wenzel, Mike Wenzel, Mike Wenzel, Marina Deuker, Marina Deuker, Maria N. Welte, Benedikt Hoeh, Felix Preisser, Till Homrich, Volkhard A. J. Kempf, Volkhard A. J. Kempf, Volkhard A. J. Kempf, Michael Hogardt, Michael Hogardt, Michael Hogardt, Philipp Mandel, Pierre I. Karakiewicz, Felix K. H. Chun, Luis A. Kluth, Luis A. Kluth   +19 more
doaj   +1 more source

Improved risk scoring systems for colorectal cancer screening in Shanghai, China

Cancer Medicine, 2022
Background An optimal risk‐scoring system enables more targeted offers for colonoscopy in colorectal cancer (CRC) screening. This analysis aims to develop and validate scoring systems using parametric and non‐parametric methods for average‐risk ...
Wei‐Miao Wu, Kai Gu, Yi‐Hui Yang, Ping‐Ping Bao, Yang‐Ming Gong, Yan Shi, Wang‐Hong Xu, Chen Fu   +7 more
doaj   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

A simplified clinical risk score predicts the need for early endoscopy in non-variceal upper gastrointestinal bleeding.

, 2014
Background: Pre-endoscopic triage of patients who require an early upper endoscopy can improve management of patients with non-variceal upper gastrointestinal bleeding. Aims: To validate a new simplified clinical score (T-score) to assess the need of an
Riccio E, Anderloni A, Vassallo R, Di Paolo MC, Caserta L, Tammaro L, T. Score Validation Study Group, Zullo A, Hassan C, STURNIOLO, GIACOMO, Natali A, Buda A   +11 more
core   +1 more source

DNA Repair-Based Gene Expression Signature and Distinct Molecular Subtypes for Prediction of Clinical Outcomes in Lung Adenocarcinoma

Frontiers in Medicine, 2020
Objective: To conduct a robust prognostic gene expression signature and characterize molecular subtypes with distinct clinical characteristics for lung adenocarcinoma (LUAD).Methods: Based on DNA repair genes from the GSEA database, a prognostic ...
Bin Hu, Di Liu, Yinqiang Liu, Zhixi Li
doaj   +1 more source

An aberrant DNA methylation signature for predicting the prognosis of head and neck squamous cell carcinoma

Cancer Medicine, 2021
Head and neck squamous cell carcinoma (HNSCC) is a common malignancy worldwide with a poor prognosis. DNA methylation is an epigenetic modification that plays a critical role in the etiology and pathogenesis of HNSCC. The current study aimed to develop a
Dayang Chen, Mengmeng Wang, Ying Guo, Wei Wu, Xiang Ji, Xiaowen Dou, Huamei Tang, Zengyan Zong, Xiuming Zhang, Dan Xiong   +9 more
doaj   +1 more source

Identification of Risk Factors and Development of Predictive Risk Score Model for Mortality after Open Ruptured Abdominal Aortic Aneurysm Repair

Medicina, 2022
Background and Objectives: Despite the relatively large number of publications concerning the validation of these models, there is currently no solid evidence that they can be used with absolute precision to predict survival. The goal of this study is to
Ivan Tomic, Petar Zlatanovic, Miroslav Markovic, Milos Sladojevic, Perica Mutavdzic, Ranko Trailovic, Ksenija Jovanovic, David Matejevic, Biljana Milicic, Lazar Davidovic   +9 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Clinical Risk Score for Prediction of Urgency in Carotid Cavernous Sinus Fistulas

, 2023
Pawasoot Supasai, Kanwasee Kanjana, Yosanan Yospaiboon KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Yosanan Yospaiboon, KKU Eye Center, Department of Ophthalmology, Faculty of ...
Supasai P, Kanjana K, Yospaiboon Y
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