Results 61 to 70 of about 3,593,757 (358)
Multi-Polygenic Risk Score Prediction Model for Bipolar Disorder
, 2019 Bipolar disorder (BP), a severe mental disorder characterized by recurring manic and depressive episodes, has been shown to have a strong genetic underpinning.
Mize, Travis
core +1 more source
Risk scoring in surgical patients [PDF]
Journal of British Surgery, 1999 Abstract Background A large number of scoring systems for assessing a patient's risk of complications or death has been developed over recent years. This is a review of those that are of relevance to general surgeons.
L. de Cossart, Helen Jones
openaire +2 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Frontiers in Oncology, 2021 Clear cell renal cell carcinoma (ccRCC) carrying wild-type Von Hippel–Lindau (VHL) tumor suppressor are more invasive and of high morbidity. Concurrently, competing endogenous RNA (ceRNA) network has been suggested to play an important role in ccRCC ...
Rui Zhu +11 more
doaj +1 more source
Anxiety Associated With Increased Risk for Emergency Department Recidivism in Patients With Low-Risk Chest Pain [PDF]
, 2018 Anxiety contributes to the chest pain symptom complex in 30% to 40% of patients with low-risk chest pain seen in the emergency department (ED). The validated Hospital Anxiety Depression Scale-Anxiety subscale (HADS-A) has been used as an anxiety ...
Fry, Colin +5 more
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Frontiers in Genetics, 2022 Background: Colorectal cancer (CRC) is the third most frequently diagnosed malignancy and the fourth leading cause of cancer-related death among common tumors in the world.
Zhongsheng Feng +3 more
doaj +1 more source
The Positive Thinking Skills Scale: A Screening Measure for Early Identification of Depressive Thoughts [PDF]
, 2017 Background Depression is currently considered the second leading cause of disability worldwide. Positive thinking is a cognitive process that helps individuals to deal with problems more effectively, and has been suggested as a useful strategy for coping
Bekhet, Abir K. +1 more
core +2 more sources
Signature of immune-related metabolic genes predicts the prognosis of hepatocellular carcinoma
Frontiers in ImmunologyIntroductionThe majority of liver cancer cases (90%) are attributed to hepatocellular carcinoma (HCC), which exhibits significant heterogeneity and an unfavorable prognosis.
Weibin Zhuo +13 more
doaj +1 more source