Results 81 to 90 of about 8,656,301 (259)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cardiac risk stratification: Role of the coronary calcium score

, 2010
Rakesh K Sharma1, Rajiv K Sharma1, Donald J Voelker1, Vibhuti N Singh2, Deepak Pahuja3, Teresa Nash1, Hanumanth K Reddy11Medical Center of South Arkansas, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Bayfront Medical Center, St ...
Donald J Voelker, Rakesh K Sharma, et al, Rajiv K Sharma   +3 more
core  

Risk of Cardiovascular Events Using the SMART Polyvascular Disease Risk Score

JACC: Advances
:: Background: Secondary Manifestations of Arterial Disease (SMART) risk score–based projection of risk for cardiovascular (CV) events can help devise risk mitigation strategies. Objectives: The objective of the study was to analyze the use of the SMART
Subhash Banerjee, MD, Anand Gupta, MBBS, MPH, Minseob Jeong, MD, David Fernandez Vazquez, MD, Shuaib Abdullah, MD, Bradley R. Grimsley, MD, Rohit J. Parmar, MD, Vishal Ahuja, PhD, Robert C. Stoler, MD, Ambarish Pandey, MD   +9 more
doaj   +1 more source

Comparison of ACUITY, CRUSADE, and GRACE Risk Scales for Predicting Clinical Outcomes in Patients Treated with Dual-Antiplatelet Therapy

TH Open, 2018
Several reliable scales have been proposed for the management and prognosis in patients with acute coronary syndromes (ACS) treated with dual-antiplatelet therapy (DAPT).
Sun Young Choi, Moo Hyun Kim, Victor Serebruany   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

LC risk score – development and evaluation of a scale for assessing the risk of developing long COVID

Introduction The aim of the study was to create a valuable practical tool for evaluating the risk of developing long COVID. Material and methods 1150 patients from the Polish STOP-COVID registry (PoLoCOV study) were used to develop the risk score.
Banach, Maciej, Agnieszka Mastalerz-Migas, Babicki, Mateusz, Piotr Jankowski, Jankowski, Piotr, Mateusz Lejawa, Żaneta Kałuzińska-Kołat, Mateusz Babicki, Kapusta, Joanna, Kałuzińska-Kołat, Żaneta, Maciej Banach, Lejawa, Mateusz, Chudzik, Michal, Michal Chudzik, Tadeusz Osadnik, Damian Kołat, Joanna Kapusta, Mastalerz-Migas, Agnieszka, Osadnik, Tadeusz, Kołat, Damian   +19 more
core   +1 more source

Prediction model of rehospitalization and mortality in heart failure patients with preserved and mildly reduced ejection fraction: the AD2NNER risk score

Frontiers in Cardiovascular Medicine
AimsThis study aimed to identify predictors of heart failure (HF) rehospitalization and explore their association with mortality in patients with preserved (HFpEF), and mildly reduced (HFmrEF) ejection fraction, leading to the development of a ...
Flavia-Mihaela Stoiculescu, Flavia-Mihaela Stoiculescu, Diana-Ruxandra Hădăreanu, Diana-Ruxandra Hădăreanu, Călin-Dinu Hădăreanu, Călin-Dinu Hădăreanu, Ionuț Donoiu, Ionuț Donoiu, Octavian Istrătoaie, Octavian Istrătoaie, Victor-Cornel Raicea, Victor-Cornel Raicea, Cristina Florescu, Cristina Florescu   +13 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Cardiovascular disease risk score prediction models for women and its applicability to Asians

, 2014
Louise GH Goh,1 Satvinder S Dhaliwal,1 Timothy A Welborn,2 Peter L Thompson,2–4 Bruce R Maycock,1 Deborah A Kerr,1 Andy H Lee,1 Dean Bertolatti,1 Karin M Clark,1 Rakhshanda Naheed,1 Ranil Coorey,1 Phillip R Della5 1School of Public Health, Curtin ...
Goh LGH, Dhaliwal SS, Kerr DA, Lee AH, Coorey R, Thompson PL, Clark KM, Maycock BR, Della PR, Bertolatti D, Welborn TA, Naheed R   +11 more
core  

A novel RNA sequencing‐based miRNA signature predicts with recurrence and outcome of hepatocellular carcinoma

Molecular Oncology, 2018
Hepatocellular carcinoma (HCC) is the fifth most common type of cancer and the second leading cause of cancer‐related deaths worldwide. Given that the rate of HCC recurrence 5 years after liver resection is as high as 70%, patient with HCC typically has ...
Fumao Bai, Huaibin Zhou, Mengni Ma, Chen Guan, Jianxin Lyu, Qing H. Meng   +5 more
doaj   +1 more source