Results 61 to 70 of about 8,656,301 (259)
BackgroundGlioma is one of the most common tumors, characterized by a high incidence rate and mortality, posing a formidable global health challenge. Palmitoylation represents a significant post-translational modification that holds a pivotal role in the
Jihao Xue +9 more
doaj +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
The Admit-AF risk score: A clinical risk score for predicting hospital admissions in patients with atrial fibrillation. [PDF]
Aims To develop and externally validate a risk score for all-cause hospital admissions in patients with atrial fibrillation. Methods and results We used a prospective cohort of 2387 patients with established atrial fibrillation as derivation ...
Osswald, Stefan +17 more
core +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery—development and validation of a risk score and effect of acute kidney injury on survival:observational cohort study [PDF]
Objective: To develop and externally validate a risk score to predict post-operative Acute Kidney Injury (AKI) in patients undergoing orthopaedic surgery and to examine the impact of AKI on both short and long term survival.
Deshmukh, Harshal +20 more
core +1 more source
Objective Hip fractures in elderly patients are a major public health concern, associated with high morbidity and mortality. Early identification of high‐risk patients is crucial to guide clinical decision‐making, optimize resource allocation, and ...
Marcello Covino +8 more
doaj +1 more source
ObjectiveThis study aimed to develop and validate a novel risk score for death within the next 3 months in patients with maintenance hemodialysis (MHD).MethodsAll the data were derived in the Wuhan Hemodialysis Quality Control Center and were divided ...
Li Cheng +8 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Background High-risk percutaneous coronary intervention (HRPCI) procedures supported by percutaneous left ventricular assist devices (pLVAD) are increasingly common, but existing PCI risk scores were developed in patients across the risk spectrum ...
Redfors, Björn +32 more
core +1 more source

