Results 81 to 90 of about 3,593,757 (358)

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Multivariate risk assessment and risk score cards in hypertension

open access: yesVascular Health and Risk Management, 2007
Giuliano Tocci1, Valentina Valenti1, Sebastiamo Sciarretta1, Massimo Volpe1,21Cardiology, II Faculty of Medicine, University of Rome “La Sapienza”, Sant’Andrea Hospital, Rome; 2IRCCS Neuromed – Pozzilli (IS), Italy Abstract ...
Giuliano Tocci   +3 more
doaj  

Penerapan Metode Job Safety Analysis and Risk Score untuk Meningkatkan Keselamatan dan Kesehatan Kerja pada Departemen Printing, Sewing dan Assembly PT. PAI, Bandung (Suatu Pendekatan Participatory Ergonomic)

open access: yesJurnal Kesehatan, 2018
The footwear industry problem lies in the working environment and facilities that do not meet the standards for the health and safety of workers, necessary improvements must be made.
Paulus Sukapto   +2 more
doaj   +1 more source

Risk Assessment for Venous Thromboembolism in Chemotherapy-Treated Ambulatory Cancer Patients: A Machine Learning Approach [PDF]

open access: yes, 2017
OBJECTIVE: To design a precision medicine approach aimed at exploiting significant patterns in data, in order to produce venous thromboembolism (VTE) risk predictors for cancer outpatients that might be of advantage over the currently recommended model ...
Ferroni, Patrizia   +6 more
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Robust pyroptosis risk score guides the treatment options and predicts the prognosis of bladder carcinoma

open access: yesFrontiers in Immunology, 2022
BackgroundBladder carcinoma (BLCA) is a heterogeneous disease that makes it difficult to achieve proper individual treatment and predict prognosis. This study aimed to develop a risk score from a new perspective of pyroptosis and guide accurate treatment
Dingshan Deng   +15 more
doaj   +1 more source

Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2015
Identifying patients at risk of future severe asthma exacerbations, those whose asthma might be less treatment responsive, or both might guide treatment selection.We sought to investigate predictors for failure to achieve Global Initiative for Asthma (GINA)-defined good current asthma control and severe exacerbations on treatment and to develop a ...
Bateman, Eric D   +10 more
openaire   +5 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Identification and Validation of Prognostic Model for Pancreatic Ductal Adenocarcinoma Based on Necroptosis-Related Genes

open access: yesFrontiers in Genetics, 2022
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors with a poor prognosis. Recently, necroptosis has been reported to participate in the progression of multiple tumors.
Haoran Xie   +13 more
doaj   +1 more source

Mediterranean diet adherence and synergy with acute myocardial infarction and its determinants. a multicenter case-control study in Italy. [PDF]

open access: yes, 2018
Cardiovascular diseases are the leading causes of mortality and morbidity in Western countries. The possible synergistic effect of poor adherence to a Mediterranean diet (MD) and other risk factors for acute myocardial infarction (AMI) such as ...
Agati, L   +10 more
core   +1 more source

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