Active Regression by Stratification [PDF]
S. Sabato and R. Munos, "Active Regression by Stratification",
Advances in Neural Information Processing Systems (NIPS) 469-477, 2014, 2014 We propose a new active learning algorithm for parametric linear regression with random design. We provide finite sample convergence guarantees for general distributions in the misspecified model. This is the first active learner for this setting that provably can improve over passive learning.
arxiv
Heart rate adjustment of exercise-induced ST segment depression. Improved risk stratification in the Framingham Offspring Study. [PDF]
, 1991 Peter M. Okin +3 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie +4 more
wiley +1 more source
Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez +15 more
wiley +1 more source
How to Do It: Utilizing Risk Stratification to Evaluate Outcomes in Adult Open-Heart Operations [PDF]
, 1992 Timothy A. Dickinson
openalex +1 more source
Early Risk Assessment Model for ICA Timing Strategy in Unstable Angina Patients Using Multi-Modal Machine Learning [PDF]
arXivBackground: Invasive coronary arteriography (ICA) is recognized as the gold standard for diagnosing cardiovascular diseases, including unstable angina (UA). The challenge lies in determining the optimal timing for ICA in UA patients, balancing the need for revascularization in high-risk patients against the potential complications in low-risk ones ...
arxiv
Liraglutide for idiopathic intracranial hypertension: a real‐world propensity score‐matched study
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Idiopathic intracranial hypertension (IIH) is a neurological disorder predominantly affecting young women with obesity, characterized by elevated intracranial pressure. While current treatments include weight loss counseling, medical therapies, and surgical interventions, their limitations necessitate exploring novel therapeutic ...
Ahmed Y. Azzam +13 more
wiley +1 more source
Handling rescue therapy in myasthenia gravis clinical trials: why it matters and why you should care
Annals of Clinical and Translational Neurology, EarlyView.Abstract Myasthenia gravis (MG) clinical trials typically allow rescue therapy during follow‐up in the event of marked worsening of MG symptoms. Failure to appropriately address rescue therapy in defining treatment effects and planning statistical analyses may yield biased estimates, increase false positive rates, or decrease statistical power – all of
Justin M. Leach +3 more
wiley +1 more source
Risk stratification with a point-of-care cardiac troponin T test in acute myocardial infarction [PDF]
, 1999 E. Magnus Ohman +10 more
openalex +1 more source