Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification
Ceramides are bioactive lipids that have an important role in many cellular functions such as apoptosis and inflammation. During the past decade emerging clinical data have shown that ceramides are not only of great biochemical interest but may also have
M. Hilvo+4 more
semanticscholar +1 more source
Framingham Risk Stratification of Middle-Aged Migraineurs
Introduction. Migraine is a common primary headache disorder involving about 10-15% of the whole population. Several epidemiological and prospective studies showed a link between migraine (especially migraine with aura) and cardio- and cerebrovascular ...
Gyula Bank+8 more
doaj +1 more source
Novel decision-theoretic and risk-stratification metrics of predictive performance: Application to deciding who should undergo genetic testing [PDF]
Currently, women are referred for BRCA1/2 mutation-testing only if their family-history of breast/ovarian cancer implies that their risk of carrying a mutation exceeds 10\%. However, as mutation-testing costs fall, prominent voices have called for testing all women, which would strain clinical resources by testing millions of women, almost all of whom ...
arxiv
Transformer-based unsupervised patient representation learning based on medical claims for risk stratification and analysis [PDF]
The claims data, containing medical codes, services information, and incurred expenditure, can be a good resource for estimating an individual's health condition and medical risk level. In this study, we developed Transformer-based Multimodal AutoEncoder (TMAE), an unsupervised learning framework that can learn efficient patient representation by ...
arxiv
Cardioverting acute atrial fibrillation and the risk of thromboembolism: not all patients are created equal [PDF]
Current guidelines support the well-established clinical practice that patients who present with atrial fibrillation (AF) of less than 48 hours duration should be considered for cardioversion, even in the absence of pre-existing anticoagulation. However,
Rankin, Alastair J., Rankin, Stephen H.
core +1 more source
Stabilized Sparse Ordinal Regression for Medical Risk Stratification [PDF]
The recent wide adoption of Electronic Medical Records (EMR) presents great opportunities and challenges for data mining. The EMR data is largely temporal, often noisy, irregular and high dimensional. This paper constructs a novel ordinal regression framework for predicting medical risk stratification from EMR.
arxiv +1 more source
Risk stratification of older patients [PDF]
Cardiovascular disease is a growing global health threat due in part to demographic shifts, in particular the growing elderly population in which cardiovascular disease is highly likely to develop. Older individuals have numerous coexisting conditions that contribute to increased risk for morbidity and mortality.
openaire +2 more sources
Multimodality Imaging in Hypertrophic Cardiomyopathy for Risk Stratification
Supplemental Digital Content is available in the text. In hypertrophic cardiomyopathy, multimodality imaging is crucial to confirm diagnosis, assess for presence and mechanism of left ventricular outflow tract obstruction, and risk stratification for ...
A. Tower-Rader+4 more
semanticscholar +1 more source
Chronic lymphocytic leukemia: 2020 update on diagnosis, risk stratification and treatment
Chronic lymphocytic leukemia (CLL) is the commonest leukemia in western countries. The disease typically occurs in elderly patients and has a highly variable clinical course.
M. Hallek
semanticscholar +1 more source
Epigenetics in diagnosis, prognostic assessment and treatment of cancer:An update [PDF]
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epigenetic changes for neoplastic cells has allowed the identification of diagnostic, prognostic and predictive biomarkers for a number of solid tumors and ...
Briasoulis, Evangelos+4 more
core +4 more sources